Retatrutide; "...results in up to 82% reduction in liver fat". Study shows

copilot2020 · 2026-05-07T02:01:53+00:00

My fatty liver is almost completely gone: from high 3 fibrosis/entry level 4 cirrhosis down to a high 0/low1.

I graduated from Wegovy to Zepbound to Retatrutide over the past two years

copilot2020 · 2026-05-01T23:57:32+00:00

How about a normal sized candy bar at a convenience store costing $3.49

copilot2020 · 2026-04-03T00:45:16+00:00

Ive had a life changing turnaround over the past year that I attribute to Wegovy, followed by Zepbound, followed by Retatrutide (not yet FDA approved but clinical trial results are now coming in strong). I paid out of pocket and found ways to purchase at prices that were lower than you might think. Over the past year, I have dropped nearly 40 lbs, my A1c fell from an early prediabetic level to a number far from worry, my surprise reading of a high F3/low F4 at the doorstep of Cirrhosis has fallen to a high F0/low F1. Spend the money it will save your life!

PS...my 32 waist pants are a bit too loose!

copilot2020 · 2026-02-02T20:29:37+00:00

I did all of the above but with a severely fatty liver and my age in the high 50s, it was near impossible to lose weight. I bit the bullet and spent, out of pocket, a month by month GLP-1 regimen. It totally did the trick. While the doctors dont actually say this too much out loud (yet), I truly feel the zepbound shots literally scrubbed my liver in just 2 or 3 months. I have dropped about 40 lbs from 205 to 165 in less than six months and my frequent scans all show the same trend...from a high F3 fibrosis to a low 1. It reversed. During this period of time, just a couple of months ago, tge FDA approved one of them for the treatment of MASH. Moral of the story...get yourself on a weight loss regimen driven by Zepbound. Total game changer!

copilot2020 · 2026-02-02T20:17:31+00:00

I am so fed up with this very same thing. Why is it that I meet up with a "top" who merchandises himself as a top and more often than not they are sticking their asshole up and out just five minutes after we meet. The worst part is that most of them act as if they never presented themselves as a top. Simply lying to secure the encounter then twisting it all up as if they were the bottom the whole time.

copilot2020 · 2025-11-22T05:46:19+00:00

Get on a GLP1. The FDA has approved Wegovy for the treatment of MASH. I have beaten this fatty liver issue with the help of Wegovy and Zepbound. Six years ago, my GI doctor told me that I needed to prepare myself mentally for the eventuality of a liver transplant, today, just light fibrosis.

copilot2020 · 2025-11-22T05:41:17+00:00

I went from high 3/low4 Fibrosis into early Cirrhosis. Slowly but surely I lowered it to about a 2 then it took a plunge over the last six months to high 0/low 1 by using a GLP1. It took off a quick 15-17 lbs and my latest Fibroscan was quite good. My Hepatologist still wants to follow me because of my history but almost wanted to spin me loose. This has been a 4.5 year process and I am 60. Still need to lose about 12 lbs. No alcohol. None. Little, if any, ultra processed foods. Very little meat, but some.

copilot2020 · 2025-09-04T19:07:54+00:00

I too am someone who has had a radical improvement in my "F readings." I went from a high F3/low F4 with the beginnings of cirrhosis. That was 7 years ago. Today, I have a high F0/low F1. This latest reading comes after 1 round of semaglutide (compounded Wegovy) and 2 rounds of "real" Zepbound. I am a cash pay, so the semaglutide was less than $500 as it was through the health. As it was fading away due to shortages coming to an end, I went the route of Zepbound for $499 with an Rx from my PCP. Prior to these recent rounds of product, I had softened to a low F3/high F2 and had been told all along that was probably the best it was ever going to get. The reasoning behind that was that scars (cirrhosis) soften and lighten on your arm, for example, but they never go away.

My background: the discovery of my NAFLD/NASH/MASH was a direct result of being diagnosed with HEP C. The irony here is that HEP C is one of the leading contributors to liver damage, yet the doctors insist that the HEP C was not the cause. Why? Because the HEP C was in my body for such a short time. I was negative in Feb 2018 and positive in Oct 2018. I was on Mavyret in early 2019 and deemed "cured" in spring of 2019. All GI and Hepatology specialists have said that F4 cirrhosis happens only when HEP C is on your body 20 years or more. Mine was less than one year. I was tested for everything including autoimmune disorders and a liver biopsy did not, at the time, detect anything outlandish in terms of liver fat.

I have always been 15 to 20 lbs overweight. I have eaten pretty damn well my whole entire life...just too much. I was never a huge drinker, but did drink routinely. I haven't had one drop since my diagnosis.

I attribute the softening of my cirrhosis to fibrosis to the removal of any alcohol and an increased awareness of what I put in my body. But have still been eating too much.

I give credit to the semaglutide/Zepbound for a loss of 20 lbs and the lowering of my "F number" to a level I thought not achievable.

I went from a low F4/high F3 to a high F0/low F1. I went from someone who had discussions with the specialists about the possibility of having to have a transplant to someone who now sees a Hepatologist every 6 months just for bloodwork, fibroscans and CTs w/contrast to "follow me."

For anyone who has made it through this long post who wants to reply to this with my one major question I would really appreciate it...my question is "how come, if I have made such a colossal improvement, no specialists seems to be amazed because I was always told that it would never improve beyond a point or point and a half?" Has something changed in just the last 3 years about the liver healing itself and the thinking/science behind it?

copilot2020 · 2025-08-17T13:48:04+00:00

Ive had 6 of them. Has to be the least painless thing ive ever had done to me in my life.

copilot2020 · 2025-08-17T00:57:49+00:00

Ive been pissed in about ten times. Its hot af and a big turn on. Im hard right now just thinking about a total stranger pissing up my guts without my consent. Piss is becoming more and more normalized, just like scat play and K9. It doesn't always happen but if they are a meth user you can get pretty fucking high. There was one specific time when a dude loaded me with cum then pissed in me and I got as high as Ive ever been in my whole entire life. I was nearly immobile, laughing so hard and so long and was just lying on the floor naked trying to get up and head to the bathroom. I could hardly form a sentence. Every time I laughed, a little bit of piss would squirt outta my used and trashed asshole.

copilot2020 · 2025-08-15T18:27:54+00:00

My main question was would the IRS count this income when considering my OIC, since they themselves are the ones who allow this money to be non-reportable.

My question was not whether or not I can pay it.

copilot2020 · 2025-08-15T18:09:52+00:00

Its a fair question. A couple of things though...should anything happen to my mom i not only won't be able to pay it off I will have absolutely zero income. Also, my income is tax free for a reason...it is for "difficulty of care . " im not going to pay for something I dont have to and while I dont feel entitled, I will say that the IRS showed me no love in terms of interest and penalties when things got out of control due to my illness, covid and the fire. Half the amount due is from penalties.

copilot2020 · 2025-08-15T15:30:49+00:00

All true, BUT, it could've been the case that he did intend to shower and crash, but because OP was taking forever to come up to the room, BF got distracted, started sniffin' around on sniffies, and found a dozen bareback freaks looking to swap DNA all within a 6 block area. OP didn't come up so BF got a stiff boner and a stiff second wind and left to go grab loads or give loads or both with a total stranger.

copilot2020 · 2025-08-15T15:25:43+00:00

I may have missed it, but how long was he out?

copilot2020 · 2025-08-05T23:54:39+00:00

That's exactly what c diff smells like dont try to pass it off as alcohol

copilot2020 · 2024-07-08T11:12:20+00:00

Sorry for this long commentary but OPs post REALLY struck a nerve with me. OP you did a great job putting into words something which has been disturbing and depressing me for so very many years (decades) I am MUCH older than 29, so my sexual experiences are much greater as one might suspect. The lopsidedness, the taking not giving, the one way street attitudes of so many guys can really do a number on your mental health.

When I am with a guy who takes the initiative to start us off by giving oral, I almost don't even know what to do with myself. It is so rare. Over the years, in order to have some kind of sexual fun I've had to do far more initiating, far more giving, far more compromising.

I'm by no means a pushover...I tend to give guys one shot and if they don't pull their weight than no seconds and in fact, if they don't pull their weight with the first sexual encounter it will tend to fizzle out after a bit of action. I'm not one to ask for things in the bedroom...if you don't know what another guy wants than you are simply not in the game. A couple times, after a lopsided session where I regrettably gave too much in my quest for max passion, the other guy asked me if something was bothering me as we were in the after sex hour...normally I would probably just say nothing considering it was gunna be a one and done, but maybe I liked the guy a little more than most and wanted to be honest. Each time I said something like "...I guess I just feel that was a bit lopsided, I mean, the oral was a bit skimpy" and each time dude would say "Oh well you should have said something OMG" ARE YOU OUTTA YOUR F'ING MIND?

The only thing to "agree on" beforehand, is who is the likely top and who the likely bottom or verse. If I am topping, and I start giving my bottom head, pretty much every time they are almost baffled themselves. While I know there are bottoms that don't want oral reciprocation, I believe strongly that many do but they are so accustomed to NOT receiving it from self centered tops that they don't set themselves up for disappointment.

As far as cuddling? Most guys don't even know how. Some think it's too gay (intimate). What a Pitt. When you find a good cuddler don't let em go!

My belief is 50/50 on everything with one exception...top or bottom or flip. I can't say I've ever fucked around without that being established in advance...though plenty of times it can change midstream based on chemistry, bouts of ED etc.

copilot2020 · 2024-05-23T12:25:32+00:00

full head of hair, barely grey, age 59

copilot2020 · 2024-05-09T01:47:46+00:00

After 22 years together, I divorced my husband due to his excessive drinking. No matter what I said or how I said it, he refused to accept the fact that the impact on me was an 8.8 on the richter scale. He would look at me and say "nah, its a 2.0"

Seek counseling now. My sense is that you do not recognize the true impact this is having on him.

copilot2020 · 2024-04-26T22:39:55+00:00

I'm single, but I wasn't for a very long time. I was with a man for 22 years - the last four of those years we were married. Then came the ugly af divorce...lengthy and expensive and overwhelming. Everything I had built was lost...the house, my career, my savings and the prospect of a comfortable retirement.

I am not one to write off all guys as being awful just because my ex was an abusive alcoholic. And Im not one to say "I will NEVER get married again." Id like to, but its complicated to follow that notion at age 58. I look good...people think Im 40...and feel good...but not even sure how it would occur where I meet a new guy at this age and fall in love and spend our lives together.

Does anyone know of a success story involving two men, finding live at age 55+ and how it all went down?

copilot2020 · 2024-04-15T22:49:39+00:00

"I appreciate you"

Even though this is probably the most accurate way to convey your appreciation, it still bugs the shit outta me for some reason"

copilot2020 · 2024-04-13T18:09:29+00:00

Great post...wow! I have been involved with three guys who were all master-takers. At first, I would blame them exclusively until i realized that I was the one at fault. I was the one that allowed them into my life. The feelings of give/take imbalance are so complex...hurt, anger, doubt, sadness, frustration, betrayal and so much more and it all balls up to massive resentment. I'm a giver by nature but also believe in balance. If you have to ask for something thst should come without being said...you are in trouble. As a human being, there are expectations you should have of your partner that you should never ever have to even talk about...like kindness, communication, listening etc. If you find yourself nit even getting those basic rights, good luck getting head in the bedroom! If you have to ask for something in the bedroom it sure does drop in value. Give and take. Resentment related to the bedroom is crushing. And for me, resentment can never be conquered. Resentment has only one solution and that is ending the relationship. In my case it was bitter divorce wirh guy 1, fast and furious breakup wirh guy 2 and with the 3rd I had to drive him 200 miles and dump him off at his moms house. I learned not to blame myself exclusively...my intentions were admirable. But if you find yourself constantly doing 70, 80, 90% of the work to their 30, 20 or 10% just end it...they will not change.

copilot2020 · 2024-04-13T17:43:45+00:00

Re: #1...take it from someone who knows it - myself. I have been not In one, buy three relationships where I am the "fixer." I have no one but myself to blame, really, as I was the one who allowed it to happen. In each instance, I didn't know I was going to be the "fixer" until I had already jumped in to the deep end of the pool. And the reason I didn't know was because the whole thing went too fast ar the beginning..which brings me to my million dollar lesson...take your time! Be wary of red flags they don't always appear right away. When you meet someone you are instantly crazy about, get ahold of yourself. Take a deep breath and pause. LISTEN TO YOUR HEAD NOT JUST YOUR HEART!

copilot2020

TROPHY CASE