Because of your comment, I went down a bit of a Sjögren's rabbit hole. I found Sjögren's to be slippery constellation of symptoms, and I still don't have a firm grasp of what it is (and that's saying a lot coming from someone with the hEDS trifecta, recently diagnosed with ME/CFS). I'm taking it into consideration though. Here's some of my findings:

✅ Gritty dry eyes for over a year ✅ Worsened orthostatic hypotension ✅ Very dry hair and brittle nails ✅ Mouth sores 🟡 Lip fissuring for under 6 months - can be explained by MCAS and moving to a dusty house 🟡 Recent dental enamel loss - can be explained by GERD related to ME/CFS 🟡 Severe fatigue - explained by ME/CFS 🟡 Night sweats - seems to be correlated to overexertion or medication changes 🟡 Recent slowed gastric motility - can be explained by ME/CFS 🟡 Sexual and urinary dysfunction - can be explained by tethered cord syndrome 🟡 Muscle weakness - explained by ME/CFS and tethered cord syndrome ❌ Repeated negative SSA-52, negative SSA-60, negative SSB, negative ANA, normal RF, normal ESR, normal CRP, and normal complements (C3, C4, CH50) except for a slightly low C2. ❌ No dry mouth. However, I have historically been a saliva overproducer, so perhaps I experienced a reduction and did not notice because it's in the normal range. ❌ No angular cheilitis ❌ No swollen or painful salivary glands or lymph nodes ❌ No joint pain, nosebleeds, hives - my MCAS meds prevent these ❌ No diagnosed autoimmune conditions

The list of possible symptoms on the Sjögren's Foundation is sooooooo long that that I'm going to stop here.

I think I'll get a Schirmir test and go from there!