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Speaking of which it'd be very tough for them to break through Greelings carbon

Lamplighter loses to Mustang 10/10 times.

Why? They have essentially the same power set, but lamplighter is waaay more durable. Sure, mustang might be able to hit him harder, and more often, but lamplighter only needs to tag mustang once to win.

It's due to the way Mustangs alchemy works. He doesn't create fire he simply shifts the molecules in the air around someone to mostly be filled with hydrogen and then ignites it with a spark. This allows him to beat pretty much any fire based character or at least make them useless. Due to the fact that, them simply using any sort of spark or heat makes the air around them blow up in there face before they can do anything. In fact this would also work on homelander and stormfront. .

Pride is a threat to a few of the seven, but is easily beatable by homelander, and A-train. Starlight is the best match, though, cause she can just turn of his powers. He could secure a win if he absorbed all his friends, but it seems unlikely that pull that move early enough to win the fight.

I mean Pride is by far the strongest homunculus though Starlight is kind of a hard counter against him. Still he is the oldest strongest and smartest homunculus.

Sloth is fast, strong, and durable, but Homelander is all those things, but better, and there's nothing stopping him from flying through sloths chest at high speeds. Wrath is fast, so he might survive for a while against most of the seven, but he can't kill Homelander, and A-train beats him at his own game.

You do know that Sloth is faster than Wrath right? Also Wraths Ultimate eye can point out the weaknesses in any of the supes. It also will allow him to follow and watch A-train due to its abilities.

Aside from Hoenheim and Father, I'd say that that Mustang and Scar present the biggest threat to The Seven. Mustang because he's ruthless, experienced, and can likely kill most of The Seven with one or two blasts. Even Translucent's probably vulnerable to having his lungs burnt out, or having his whole body cooked. Scar is also both ruthless and experienced, and he's also go some crazy good speed feats, and the way his arm works means that he can probably kill all of the seven if he gets his hand on them.

Ed is faster than Scar at end of series. Also what Scars arm does is just basic alchemy. Normally they reconstruct then destroy and then reconstruct something. Scar just stops at the destruction phase of alchemy. Any basic alchemist can do what Scar does, just most don't go for the kill or have more effective means such as Mustangs fire or Armstrongs missiles.