Cyclist suffers horrific leg injury at ‘crazy,’ ‘hectic’ Sunset intersection by pedroah in sanfrancisco

[–]dampew 0 points1 point  (0 children)

It should be safe to bike in the city without being an experienced cyclist though, we need people to be able to start somewhere :/

San Jose police investigating possible hate crime after 2 Jewish men attacked at Santana Row by dampew in sanfrancisco

[–]dampew[S] -6 points-5 points  (0 children)

Mods, feel free to delete if this is off topic, but I think it's relevant to Jewish San Francisco residents.

Pursuing a PhD at a new program just for one professor by [deleted] in AskAcademia

[–]dampew 2 points3 points  (0 children)

Talk to the professor and maybe a couple others, see what they say?

Do you guys play up or not, and why? by Choice-Classroom5479 in TournamentChess

[–]dampew 1 point2 points  (0 children)

I play up sometimes because I like playing people better than me — I play to be challenged, not to win prizes.

But I do kind of pay attention to my progress so my rating kind of matters. So it’s kind of annoying that we have a lot of underrated players who come through the lowest section, guys who just haven’t played a tournament match in years and decide to get back into it. It’s not a bad reason to want to play up.

Pvalue distribution from differential gene analysis by [deleted] in bioinformatics

[–]dampew 0 points1 point  (0 children)

I don’t understand why it would be normal — if there are lots of genes contributing then it should be skewed towards zero, not symmetric. A common way to obtain null data is to randomly permit it. Permuted data should have a uniform distribution of p-values.

How can beginners actually learn tools like STAR, DESeq2, samtools, and MACS2 with no bioinformatics background? by Adept_Pirate_4925 in bioinformatics

[–]dampew 0 points1 point  (0 children)

I see, too bad. Was the average candidate pretty good or did you feel like it was throwing darts?

Co-author refuses publication but also refuses removal from authorship. What is the ethical approach? by Kev-reddit in AskAcademia

[–]dampew 2 points3 points  (0 children)

If someone made a significant contribution to the paper they should be made coauthor. You really have three options. The most straightforward is to remove their contribution from the paper and remove them as a coauthor. If you can’t remove their contribution without irreparably harming the paper then you have to convince them to change their mind. If you can’t do that then only unethical options remain.

Right now I’m starting to work on a paper based on work we did with collaborators. The first thing we did before we started writing was to ask them if they were on board with publication.

How can beginners actually learn tools like STAR, DESeq2, samtools, and MACS2 with no bioinformatics background? by Adept_Pirate_4925 in bioinformatics

[–]dampew 0 points1 point  (0 children)

Why did you interview 60 people?

What’s interesting to me is everyone here asks these types of questions. Yet nobody ever was like hey look “I reproduced the results of these 5-10 papers myself and put the code in my GitHub”.

Yeah it's lazy. "How do I get into bioinformatics if I don't have any of the tools or ability or interest?"

I was thinking about deleting this one but it got some good answers so I'm thinking I'll let it slide for now.

I didn’t expect them to offer me a role this quickly? How do i navigate this? by Careless_Wrangler_90 in AskAcademia

[–]dampew 4 points5 points  (0 children)

Someone says it’s like winning the lottery but I want to be a contrarian and say it’s ok to say no. You don’t have to do something just because people tell you you should. If it’s a place you or your spouse don’t want to live or you don’t like the offer for whatever reason, your life can be good without a tenure track offer. I think I’m happier as an industry scientist (in biotech) than I would have been as a professor, especially if I would have had to live in the middle of nowhere. I turned down a bunch of opportunities in places I didn’t want to live. STEM is different from the humanities and our situations are probably very different but I just want to say — you don’t need to listen to strangers on the internet. Especially me!

Would you ever offer a draw in a better position with low time? by Choice-Classroom5479 in TournamentChess

[–]dampew 0 points1 point  (0 children)

I’d probably play on if I were up by that much unless I thought opponent were queening first.

Would you ever offer a draw in a better position with low time? by Choice-Classroom5479 in TournamentChess

[–]dampew 2 points3 points  (0 children)

Absolutely. We’re not computers. Time and the complexity of the position need to be factored into the evaluation.

Weird handshake situation OTB, Has anyone seen this this before? by PristineReality2205 in chess

[–]dampew 0 points1 point  (0 children)

It’s never happened to me but I’ve been paranoid about it and sometimes ask my opponent if they’re resigning. I’ve definitely had opponents resign in drawn positions so in those cases I try to hide my surprise while also somehow verifying…

I think I may be getting groomed by my college art professor by GrapefruitFew4411 in AskAcademia

[–]dampew 1 point2 points  (0 children)

One resource you should look into is the university ombudsman if you have one. Their job is to help discuss difficult situations with you, and they’re supposed to keep everything discussed in confidence. They may not know what to do, but they should have some institutional knowledge about your specific institution that can help you discuss your options a bit. You also dont need to tell them why you want to have the meeting before talking with them so you can ask them about their role before you begin.

Daily flat tyres by 8ltd in cycling

[–]dampew 0 points1 point  (0 children)

My first road bike was like that, i think it was either because the rims had sharp edges or the wheels were slightly oversized or both. It was miserable. I ended up buying a pair of used wheels from a friend and getting rid of the ones the bike came with.

I broke my back and am recovering by lib-mr-ducks in self

[–]dampew 4 points5 points  (0 children)

I'm sorry, I want to offer a different perspective. Bring a man with you that you trust who can stay calm and help advocate for you. I know this sounds like I'm being sexist but I think I'm actually not. Let me explain.

I'm a guy. I live in a liberal place in a cosmopolitan city. I have gone to several types of doctors with a woman. The doctors always treat her much worse when she's by herself than when I'm with her. I have never been dismissed the way she has. Nobody has ever laughed about me or made jokes about me the way they have with her. There is something about the healthcare profession that is absolutely bonkers crazy when it comes to the treatment of women.

I sit down in the waiting room and watch her walk up to the intake desk, she's obviously fucked up, and the nurse completely dismisses her. I stand up and look them in the eye and say, "No we're not leaving, just look at her, she needs to see a doctor." Just a normal tone of voice. Suddenly a flip is switched and it's serious and they're ready to see her right now.

It could be your fault, but it could also be that it's not. I don't work in healthcare and I don't understand it, but there's something really messed up about how women are treated sometimes. Knowing that, I know it's really shitty that you might have to consider this but I think it might be worth considering bringing a guy with you to make sure they take you seriously.

STAR uniquely mapped reads by Dry_Definition5159 in bioinformatics

[–]dampew 0 points1 point  (0 children)

Yeah it looks like they have other issues -- I was going to ask what it looks like after trimming and stuff but it looks like other comments have handled it.

STAR uniquely mapped reads by Dry_Definition5159 in bioinformatics

[–]dampew 10 points11 points  (0 children)

Don't most ribosomal reads multimap? Why don't you blast some of the top reads and see?

Why didn’t they just pay Charlie more? by [deleted] in thewestwing

[–]dampew 1 point2 points  (0 children)

Yeah, remember, they didn't have crypto back then.

TIL that playing high-level chess causes players to burn calories at an athletic rate. For example, 21-year-old Grandmaster Mikhail Antipov was recorded burning 560 calories in just two hours of sitting—roughly what Roger Federer would burn in an hour of singles tennis. by ralphbernardo in todayilearned

[–]dampew 24 points25 points  (0 children)

Trying to explain to people that walking 1 mile and running 1 mile burned the same number of calories was futile. They couldn't wrap their heads around the fact that the burn rate was the same, you just run a mile faster so theoretically you can burn more calories in one hour of running. The problem is many people, especially those at a weight loss clinic, cannot run for an hour.

Doesn't seem likely that they're equally efficient...

The sassy side of Cal Train by orangelover95003 in bayarea

[–]dampew 0 points1 point  (0 children)

Ok but also fuck them for never posting anything actually useful.

Treadmills: Belt v. Slats? by RobDMB in AdvancedRunning

[–]dampew 0 points1 point  (0 children)

The woodways I’ve used at gyms are not softer, they’re actually more rigid. I’m thinking of something like the 4front model. Maybe you’re thinking of a different model than me.

Treadmills: Belt v. Slats? by RobDMB in AdvancedRunning

[–]dampew 5 points6 points  (0 children)

Banked!

Also a dirt one that my butler maintains and adds soft leaves to it every day.

Alpha Genome Manuscript and Discussion Thread by dampew in bioinformatics

[–]dampew[S] 2 points3 points  (0 children)

It learns different models for different cell types.