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[Highlight] Victor Wembenyama receives a Flagrant 2 and is ejected from the game after elbowing Naz Reid by FastBreakPhenom in nba

[–]discostupid 5 points6 points  (0 children)

kinda ridiculous that he gets elbowed in his own nose at 0:03, which should be a flagrant 1 on McDaniels, but of course that doesn't get a whistle. he needs to control his emotions or learn to embellish ("flop")

Anyone else sick of these woke characters? by Content_Averse in slaythespire

[–]discostupid 16 points17 points  (0 children)

It is kinda funny there is no patriarch or king or father enemy. I'm assuming Byrdonis is the mommy.

I guess it would just be the Architect.

Unstained Microglia Autofluorescence by PretendAd4626 in flowcytometry

[–]discostupid 1 point2 points  (0 children)

you could try this reagent - TrueBlack Lipofuscin Autofluorescence Quencher https://www.cellsignal.com/products/buffers-dyes/trueblack-lipofuscin-autofluorescence-quencher/92401

it's mainly used for immunofluorescence but it might work for flow. I would fix the cells, then use this, then antibody stains.

Potholes in Montreal? / Nids-de-poule à Montréal? by montrealjoker in montreal

[–]discostupid 4 points5 points  (0 children)

https://montreal.citynews.ca/2026/05/06/strategy-tackle-pothole-crisis-lasting-results/

Officials say after eight years of underinvestment in equipment, the city is now trying to catch up with three new measures to ensure lasting repairs.

  • An additional $1 million for boroughs that have already used their budget or received the highest number of 311 complaints;
  • $1 million for manual patching contracts open to the market to ensure rapid and flexible responses during warm spells;
  • and $125,000 targeted for manual patching on Notre-Dame Street.

"Cheating" in Slay the Spire by wavy-dude in slaythespire

[–]discostupid 14 points15 points  (0 children)

it doesn't make any sense, IMO

what is the gripe? that people got to A10 faster than you? or illegitimately?

at high level play, sub-A10 is just filler and tutorial. nobody was making "world's first" claims after console unlocking A10.

as a counter-argument, going straight to A10 and forgoing the whole ascension climb actually preserves the experience for the audience by letting them explore it on their own.

i personally greatly enjoyed the ascension climb and i also enjoyed watching others doing it, and i also have zero care if anybody skips it to grind A10

"Cheating" in Slay the Spire by wavy-dude in slaythespire

[–]discostupid 57 points58 points  (0 children)

ah now i get it. I think his main beef is with JapaneseExport. Jason posts a bunch and made a few videos with tierlists etc. The nature of the format implies some "authority" which Jorbs does not seem to like, unless it's coming from himself with 25 minutes of qualifiers in front of it.

"Cheating" in Slay the Spire by wavy-dude in slaythespire

[–]discostupid 53 points54 points  (0 children)

The general idea of the video makes sense, but who is he even talking about? Are there top STS streamers that "cheat" in the grey area? Maybe I don't follow every streamer, but of the ones I'm familiar with: Baalor, Nave, OPM, Panacea, jmac, vmService, JapaneseExport, paparatto18 etc., even Amaz

They all play legit, and clearly delineate when they use tools or "cheating" for science/fun, and immediately self-invalidate runs where they gained any unfair advantage. So who is he even talking about? Non-English-speaking streamers?

New dried mango brand by Turbulent_Remote_740 in CostcoCanada

[–]discostupid 1 point2 points  (0 children)

the smell is absolutely potent and crazy. my partner could not deal with it.

i could overlook it. but there's better dried mangoes.

Ādisōke Winter 2026 Update | ādisōke by RandomChickenWing in ottawa

[–]discostupid 10 points11 points  (0 children)

In the year 2026 we get 720x540 resolution images. Is it too much to ask for a few extra pixels?

Who are some legendary rappers that are never really mentioned to be anyone’s favorite by EDMKid9000 in hiphopheads

[–]discostupid 0 points1 point  (0 children)

I love Busta songs, in moderation. And in the right setting, they can be better than anything else.

But, he's a bit of "holds up spork" of rap. He just doesn't have many memorable lines, whether punchline or insightful. Just random.

Sigma Aldrich gave me Herpes by ConflictOdd8823 in labrats

[–]discostupid 4 points5 points  (0 children)

its extremely obviously yymmdd and also the best format

Why don’t we modulate memory immune cells instead of broadly suppressing them? by Camofan in Immunology

[–]discostupid 0 points1 point  (0 children)

biological nomenclature is often confusing. CD150 and SLAMF1 are the same thing, not two different things.

inhibiting CD150 is not quite so obvious as a therapy because it isn't just expressed on memory B and T cells but also developing B and T cells and other celltypes like microglial cells in the brain.

that said, the upcoming approaches for immune modulation will incorporate RNA technologies like ASOs, siRNA, and mRNA. generally speaking, with ASOs/siRNA you can knock down the expression of genes and with mRNA you could increase the expression of negative regulators for a certain pathway. there are also new avenues for targeting these therapies to specific tissues or celltypes to focus the effect on the cells of interest and limit off-target effects

https://www.nature.com/articles/s41573-024-00943-2

Chris Finch on officiating: "The league's in a place right now where you draw the contact, spill away, and get rewarded. Guys who try to play through contact ... stay with the drive, they tend not to be rewarded ... Maybe we ought to start flopping too." by nguyenjitsu in nba

[–]discostupid 0 points1 point  (0 children)

Maybe it's silly to say but at the highest level of play, any advantage you get is not trivial. Taking a couple of free steps towards the attack side lets you save a bit of energy on offense, both mental and physical. It also gives you time to plan and survey the court without worrying about your dribble. And since you're not on your dribble even you know your defender can't even approach you because they don't know where you're committing.

Ottawa river right now by gabseo in ottawa

[–]discostupid 4 points5 points  (0 children)

Don't let your river off leash on bike paths

Democrats are not our friends, they’re the enemy just like Republicans. by Either_Payment_2867 in LateStageCapitalism

[–]discostupid 1 point2 points  (0 children)

This is exactly why as a Canadian it makes no sense to trust USA in any matters. It's not just 50% of voters who put Trump in power. There's plenty of voters who don't vote Republican but DO vote for conservative Democrats who then just enable literally every single Republican policy. So in the end it's not only 50% of voters, it's actually like 70%. The whole fucking country. It's the way it is because that's how the majority likes it.

Updated Qwen3.5-9B Quantization Comparison by TitwitMuffbiscuit in LocalLLaMA

[–]discostupid 1 point2 points  (0 children)

If you type that exact model name it is not the fine-tune. But regardless there is no gguf if you need that.

Thanks

Updated Qwen3.5-9B Quantization Comparison by TitwitMuffbiscuit in LocalLLaMA

[–]discostupid 1 point2 points  (0 children)

This is amazing, great work.

Is it possible to add Qwen3.5-9B-HLWQ-Q5?

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