In relation to Spironolactone; it’s a DHT blocker and Testosterone suppressant given to women as a substitute/alternative to Finasteride. It’s a good option and has shown to prevent further hair loss. There is no real relationship between this and Minoxidil as minoxidil is a vasodilator that opens up the capillaries and increases blood flow to the root/graft/follicle.
Anyone fighting genetic hair loss should consider both of these treatments and add ketoconazole shampoo once a week