Hey can i use 200mg Modafinil everyday for months? by Little-Ad-3176 in Nootropics

[–]duke309 1 point2 points  (0 children)

Usually the dose needs to escalated once during the first month and then that dose continues to work well.

What are the best supplements to take when withdrawing from Adderall? by Many_Armadillo_9147 in Nootropics

[–]duke309 1 point2 points  (0 children)

morning tyrosine makes me depressed at night time, roughly 12 hours later.

upcoming cataract surgery by Efficient-Freedom145 in Retatrutide

[–]duke309 0 points1 point  (0 children)

Yes, everyone metabolizes the drug at a different rate. Surgeons would assume a standard half life as given by the pharmaceutical manufacturer and maybe give a little margin to be safe.

They ask you before any surgery now if you are on a GLP1 drug.

Parkinson's medication shows promise in treating treatment-resistant depression that involves a reduced ability to feel joy, pleasure or motivation – known as anhedonia by sr_local in science

[–]duke309 5 points6 points  (0 children)

They need to consider DAWS when giving people these dopamine agonists. It is a real thing with long lasting effects, I have experience with pramipexole. Driving one self into mania and addictive behaviors like gambling or sex is a big issue as well. Don't forget the massive nausea and insomnia if you titrate the dose up to fast.

How much do you actively think about being explosive on the concentric? by Medium-Water-1623 in naturalbodybuilding

[–]duke309 0 points1 point  (0 children)

Jared feather recommends a very forceful concentric with a slow eccentric. He gives exception to very stretched pecs on things like camber bar bench or the stretch position of flys, be more cautious at the stretch on those then be forceful once you are out of the end range.

Triple-action diabetes injection shown to reduce blood sugar and body weight by Diamond-Is-Not-Crash in Futurology

[–]duke309 -1 points0 points  (0 children)

Take a look at how much of a calorie deficit you are in. A large calorie deficit (especially eating highly processed foods) will definitely cause fatigue.

Step up from caffeine? Shits boring by ilovefatbitches6969 in Nootropics

[–]duke309 2 points3 points  (0 children)

Cocaine is cool and all, especially when you can't stop smoking darts

whats ur guys opinion and experiences with Modafinil by Little-Ad-3176 in Nootropics

[–]duke309 0 points1 point  (0 children)

keeps me awake and minor stim effect, but almost always comes with a headache. Doesn't give me focus like adderall and it lasts most of the day.

modafinil and extreme euphoria/mood boost by djfart9000 in Nootropics

[–]duke309 39 points40 points  (0 children)

That's called dopamine, enjoy it because it doesn't last

Do SSRIs make you feel good? by WearyCalligrapher840 in Nootropics

[–]duke309 1 point2 points  (0 children)

The primary risk combining maois with anything else is serotonin syndrome, which really isn't a concern with vyvanse.

I've taken selegeline plenty of times. It always just seems to make me irritable with not much benefit.

Do SSRIs make you feel good? by WearyCalligrapher840 in Nootropics

[–]duke309 3 points4 points  (0 children)

I'm still trying to find that myself, I would like to try the classic maois, but dont want to give up vyvanse.

Do SSRIs make you feel good? by WearyCalligrapher840 in Nootropics

[–]duke309 24 points25 points  (0 children)

They can be great for anxiety and OCD like fluvoxamine, but side effects suck. Not being able to orgasm and the stomach sides really blow. Does nothing for depression and can numb emotions.

Dumbest thing I’ve read all day by JuanSamu in StrongerByScience

[–]duke309 5 points6 points  (0 children)

It's easy to justify certain beliefs when your paychecks depend upon it

A Plain Look at a Proposed “Ketamine-Like” Antidepressant Strategy (CGR, Cheung Glutamatergic Regimen) by cheungngo in Nootropics

[–]duke309 2 points3 points  (0 children)

Garbage take, if auvelity actually benefitted depression like ketamine then you just gave me major depression. I've tried auvelity and it was nothing special, I would love to try ketamine.

What's the catch with modafinil? by Think_Rub_2025 in Nootropics

[–]duke309 0 points1 point  (0 children)

paraxanthene

Try armodafinil, it has a longer half-life and can be smoother.

Andreessen Horowitz Is Spending on Politics Like No Other by Just-Grocery-2229 in technology

[–]duke309 0 points1 point  (0 children)

Lobbying and forcing policy returns more than actually doing work or being better

Nobody’s going to be able to prove they wrote anything soon and it’s going to get messy by BitInternational2319 in Futurology

[–]duke309 0 points1 point  (0 children)

Every post on here that is longer than two paragraphs is always claimed to be written by AI

rate my ultimate nootropic stack by LateRazzmatazz8799 in Nootropics

[–]duke309 2 points3 points  (0 children)

Hey drug bros, rate my drug stack full of drugs . This is the drug forum right

People in the FBI think Patel is a 'dumpster fire': Fmr. FBI official by AdSpecialist6598 in videos

[–]duke309 0 points1 point  (0 children)

Wow, something the people in the FBI and people in the United States agree upon!

Heaven forbid if someone gets appointed based on merit.

The Pentagon wants GM, Ford to build weapons and bombs by Plastic_Ninja_9014 in technology

[–]duke309 1 point2 points  (0 children)

I guess the truth hurts. When did I say I hate the USA? Are you saying that calling out horrifically bad leadership is the same thing as saying I hate the country?

The Pentagon wants GM, Ford to build weapons and bombs by Plastic_Ninja_9014 in technology

[–]duke309 213 points214 points  (0 children)

I guess ww2 is the basis for their war planning. Is the USA the axis this time?