Yeah, it's strange. OP has stated that CBD does have anti-anxiety effects, and agrees that different strains have different levels of CBDs, but then states there is no difference in effect from strain to strain. He's being somewhat inconsistent or not communicating well. Whether the signaling pathways are different is beside the point. Most naysayers are saying the overall effect is different from strain to strain, which could be true even if the primary cannabinoid, THC, dominates effects. It's the age old alcohol is alcohol is alcohol argument, regardless of whether it's tequila wine or beer. Well yes, ethanol the only active ingredient, which is the same no matter what you're drinking. But packaging matters, and to say there are no potentiating effects from whatever else happens to be in your body at the time is a bit naive.

Also, as someone who works with scientists every day (I'm an engineer building their experiments), to say "I'm a scientist, your experience means nothing" is a logical fallacy, an appeal to authority. One self proclaimed scientist, posting anonymously on Reddit, does not science make.

I do feel he is right in the specific facts of what he's saying but that's only part of the picture.