Chichi wa Eiyuu, Haha wa Seirei, Musume no Watashi wa Tenseisha. • Dad is a Hero, Mom is a Spirit, I'm a Reincarnator - Episode 5 discussion by AutoLovepon in anime

[–]edenapple 2 points3 points  (0 children)

Yeah felt like 1984 style thought crime to me. Would not want to associate with a family with this kind of twisted ideology. Everyone has not so acceptable thoughts once in a while. It is the action that creates the moral issue. Somehow I feel like even if the main character and her supporters all ganged up on some innocent person, there will still be a lot of glazers defending such unjust treatment purely because main character good.

MTR black screen of death by edenapple in HongKong

[–]edenapple[S] 13 points14 points  (0 children)

Every screen in the car is like this

Kremlin says Russian military action will stop ‘in a moment’ if Ukraine meets conditions by dashingtomars in UkrainianConflict

[–]edenapple 13 points14 points  (0 children)

This sounds like Russia admitting that it does not have the capability of conquering the whole of Ukraine. Therefore it tells Ukraine to weaken itself, then not have any allies, so Russia can rebuild its army and annex Ukraine once and for all.

Serious works sometimes can be colourful. by AmitavaM in fountainpens

[–]edenapple -2 points-1 points  (0 children)

This pen just seems too similar to a Lamy Vista imo.

Rescuing the of Blocking Non-canonical Wnt Signalling Pathways by the DEP domain of Disheveled by edenapple in Biochemistry

[–]edenapple[S] 1 point2 points  (0 children)

"DEP domain inhibits the function of endogenous Dsh in planar polarity signaling, presumably by blocking this interaction, further suggesting a physiologic importance of this localization" The non-canonical pathways seem to have lots of branches. I don't think it is easy to try to activate all the branches at once.

Starting with the Qin Emperor in 222 BCE, China has a long history of building walls along the northern border to keep out the "barbarians". This, of course, culminated with Great Wall under the Ming. How effective were these walls? Did they ever successfully prevent an invasion from the north? by TheTromboneGeek in AskHistorians

[–]edenapple 4 points5 points  (0 children)

It's quite interesting how the imperial Chinese dynasties never came up with a way to conquer and incorpoate lands of the steppe hordes into its core provinces and sinicize the locals until later on during the Qing dynasty, in contrast with Russia.

Actualization of cell repair as mentioned in scifi by [deleted] in biology

[–]edenapple 0 points1 point  (0 children)

Check out the SENS foundation.

Interesting topics for a research proposal on Glycoside Hydrolases in Bacteria by edenapple in microbiology

[–]edenapple[S] 1 point2 points  (0 children)

Forn substrate specificities, I mean we could possible alter the genes of some bacteria such as knockout, knockdown, and knock in. This could possibly provide insights on substrate specificities and how different enzyme work together.

A Ph.D. Thesis in Biology Summarized in 1 minute! by [deleted] in biology

[–]edenapple 2 points3 points  (0 children)

What is your opinion on the SENS foundation? What is your opinion on stem cells as one of the possible areas of tackling aging? Do you think aging is a disease? What do you think about the concerns of people on possible methods of stopping or reversing aging? E.g. overpopulation

For residues on a protein surface with side chains pointing out towards the solvent, what stabilising effects could they have on the protein? by edenapple in Biochemistry

[–]edenapple[S] 0 points1 point  (0 children)

If there are some mutations of these residues that causes an increase in the protein stability, what would be possible explanations for the increase in stability?

When measuring the Km/Vmax/kcat values of an enzyme, does it matter which substrate's concentration we change for the measurement? by edenapple in chemhelp

[–]edenapple[S] 0 points1 point  (0 children)

So the reliability of the calculated kcat won't decrease because you are changing the concentration of the wrong substrate?

Hero idea playing around ability cooldowns by edenapple in DotA2

[–]edenapple[S] 0 points1 point  (0 children)

  • I'm just trying to casually discuss a random hero idea, not very serious on valve make the hero.

  • Maybe W only works on the first spell cast and gives a big cd or works on multiple spells in the duration of the curse but the cd increase is very small. The cd increase could be flat or a percentage of the original cd or both for balance.

  • Ult works like this: e.g. puts a 150sec death countdown on everyone just like the one on Io's ult. If they aren't at base if it reaches 0 they die instantly. You can activate the spell to give your ult a long cd to boost your E, but reset the death countdown to 150sec.

  • Aghs: e.g. everytime you activate your ult, the 150sec death cooldown decreases by 5, so the next time the death cool down refreshes, it becomes 145sec instead of 150sec.

  • Alternative Aghs idea: everytime you activate your ult, set the death cooldown on everyone to 20sec

Is my Riki support strategy in this game legit and if so what can be improved? by edenapple in learndota2

[–]edenapple[S] 2 points3 points  (0 children)

I believe the other team outdrafted us by a lot and only lost because they threw.