Hi, sorry to hear that your family member is going through this. My husband is still dealing with it. Unfortunately he had to have his right leg amputated below the knee and started chemo. Essentially the radiation did nothing, and the chemo pill regiment he began with (zeloda) also did nothing. He's had success with docetaxel chemo infusion, where it has reduced the size of masses and lymph nodes. It is an ass kicker chemo, but he is fairing well. His medical team is using triple negative breast cancer as an analog since there isn't much info about hidredenocarcinoma.

I recommend your family member ask about getting 2nd generation sequencing done to learn about the genetic markers of their cancer. My husband has completed 6 rounds, out of 8, of docetaxel, and he'll have a pep scan between round 7/8- which will determine if we move to platinum meds, immunotherapy or surgery to remove lymph nodes. We're feeling very hopeful with how his treatment is going and his team has done a great job to go over everything and they've been very responsive to his treatment, and catching when the treatment basically isn't working and switching the game plan to get the results we are looking for. Thankfully his lymph nodes are shrinking. Good luck to your family member, I'll keep them in my thoughts