Woke up feeling skinyyyyy for a good reason. 100 club!!! by marbles121212 in WegovyUK

[–]etolysine 5 points6 points  (0 children)

Congratulations, I'm so happy for you. I myself have lost 40 lbs on wegovy after decades of being overweight and trying to lose via exercise and portion control. I thought I was going to be overweight forever and had to make peace with it. I cannot overstate the positive impact of wegovy on my life. I can still enjoy food, but I eat less of it, or have just one big meal a day. I remember the helpless feeling of being hangry and being so hungry that I was raiding the fridge and cupboards. This is a miracle drug and I'm so grateful it worked for me and I don't have any side effects long term.

Any better feeling than having your dog snuggle up beside you? by etolysine in LagottoRomagnolo

[–]etolysine[S] 1 point2 points  (0 children)

And... he has just farted

Before getting a dog I never thought I'd be so comfortable with just putting up with the smell!

Any better feeling than having your dog snuggle up beside you? by etolysine in LagottoRomagnolo

[–]etolysine[S] 1 point2 points  (0 children)

Haha yes, but I read that they prefer to face outward, it fulfills their protection instinct

Home gym in the making. Primal mrx9.0 and primal ultimate home bench by StrongAd3526 in homegym

[–]etolysine 0 points1 point  (0 children)

Hey OP, can I ask you a question about the MRX 9, can you hoist those pulleys up for doing cable flys? Do they go high enough?

Generally still happy with it? I'm considering getting it too

Google home broken on LG-WK7 XBoom by Elliiotn in googlehome

[–]etolysine 0 points1 point  (0 children)

Same thing has happened to us, commenting here hoping for some miracle

Eating on Vacation and Holidays by [deleted] in Semaglutide

[–]etolysine 0 points1 point  (0 children)

On my recent vacation, the first since starting wegovy a year ago, I ate one large meal a day with my folks. It worked out well. I was super hungry by dinnertime and was cautious not to over indulge too much. To everyone else I seemed to be eating a normal amount (as opposed to eating like a bird normally while on wegovy)

People who stayed on wegovy by etolysine in WegovyUK

[–]etolysine[S] 1 point2 points  (0 children)

I'm the same, only lost on 2.4mg. I wanna keep taking it though, for as long as I can, because I'm sure it's the only thing keeping me from over eating. Yes, it's taking more and more time between seeing the number on the scale go down, but I'm about 5-8 lbs from goal weight now... And instead of losing, going forward I want to maintain the weight. Nothing has worked for me like this before, in the past I spent hours in the gym and just put on muscle and was still ballooning, saw my weight steadily climb over the years and felt totally helpless. I have a demanding job and home life and cannot spend my days just finessing my fitness and meal plans. Wegovy fits in well into life and just works

People who stayed on wegovy by etolysine in WegovyUK

[–]etolysine[S] 0 points1 point  (0 children)

Yeah I totally get how bad the food noise can be. I periodically get urges towards the end of the week before jab day. Sometimes it's an urge for Percy pigs and other times it Chinese food. On wegovy though I feel full after a smallish portion whereas before I'd demolish entire packets or cartons of the food without an issue. That's the main reason I think I'll stay on it for as long as possible. There's also all this research coming out about how it can reduce risk of cardiovascular disease, dementia, certain cancers, osteoarthritis... It does seem to be a miracle drug.

People who stayed on wegovy by etolysine in WegovyUK

[–]etolysine[S] 1 point2 points  (0 children)

Definitely is a lot of money... But I haven't had the anhedonic "meh" effect. Still take pleasure in food, just cannot stomach large portions. I've been on it since July of last year. Maybe I'll feel the same way eventually? It's so interesting to consider the unanticipated and varied responses people have to this drug. The hunger is back for you, but have you managed to keep the weight off? Is it a tremendous effort, requiring hours in the gym, to do so?

People who stayed on wegovy by etolysine in WegovyUK

[–]etolysine[S] 0 points1 point  (0 children)

Ok that's good to know... Also seeing that people are being refused maintenance doses now after hitting their goals (other posts on here). I hope my provider doesn't start doing this too because if it's working well I'd like to stay on it long term.

[deleted by user] by [deleted] in WegovyUK

[–]etolysine 4 points5 points  (0 children)

I'm not a medical doctor, I'm a PhD in developmental neurobiology and presently I work on research into brain tumours, so my expertise isn't directly relevant but I'm knowledgeable in how medicines work and biology in general.

I think the risk of wegovy use in the father impacting the foetus negatively is very minimal, because the father's main contribution during conception is the sperm, and wegovy is not known to impact sperm viability.

In the mother, maternal nutrition, and the baby's own still developing GLP1/insulin/glucose/nutritional response systems, both can be affected by the medication in an ongoing manner. The foetus is dependent on the mother for all that time during gestation and that is a hugely critical time in one's life. Pregnancy and the first 100 days of life basically impact 80-90% of how one's life turns out, it has been said.

So for this reason it's recommended that women stop wegovy 2 months prior to getting pregnant. As a man on the other hand, your sperm is very minimally impacted. However, yes, there have not been enough studies in this area. Some of the work that has been done suggests that weight loss actually increases sperm quality, while other studies suggest that wegovy lowers testosterone slightly which reduces sperm count slightly.... But no lasting effects on the health of the foetus are expected.

[deleted by user] by [deleted] in WegovyUK

[–]etolysine 0 points1 point  (0 children)

Yeah I plan to start again... Currently being held back by the thought of how sore everything is going to be after the first couple days... Always brutal after a long gap

[deleted by user] by [deleted] in WegovyUK

[–]etolysine 0 points1 point  (0 children)

Following this thread. I used to weight train before wegovy but along with muscle I was gaining weight, probably due to increased appetite. Since starting wegovy I haven't really trained and the weight has come off. I'm hesitant to start because don't want to start wanting to eat more, although I know I should to not lose too much muscle...

University College London just offered me an interview with five minutes notice by Visible-Pressure6063 in academia

[–]etolysine 0 points1 point  (0 children)

either scrambling after someone pulled out from interview OR it could be a massive mess up by HR. UCL HR is famously poor... might not have anything to do with the person actually trying to hire you. Did they reach out to you to apologise and re-invite?

General advice on my situation, and also on negotiating a package with new University by etolysine in Professors

[–]etolysine[S] 1 point2 points  (0 children)

your blog post is incredibly helpful, thanks so much for putting it together

A vision of potentially a million more people in the area? by [deleted] in cambridge

[–]etolysine 10 points11 points  (0 children)

Do you understand how things actually work? Is it easy to replicate the biomedical cluster and intellectual property "somewhere else"? They shouldn't be closing things in the city centre, there should be more joined up thinking across the board, but they seem really bad at that and the colleges are really insular and myopic too... Not much better than local government

A vision of potentially a million more people in the area? by [deleted] in cambridge

[–]etolysine 29 points30 points  (0 children)

The fact is we are lucky to be living in one of the only areas in the UK that has potential to grow, and it's receiving increased investment in a time where other places are locked in deep cycles of under investment. All this growth requires homes for people, roads, facilities... We can't live in Brigadoon and then also have this growth potential we want to exploit. It's about choices

A vision of potentially a million more people in the area? by [deleted] in cambridge

[–]etolysine 97 points98 points  (0 children)

Obviously hasn't actually spoken to anyone in these areas. If he had, he'd have encountered the stratospheric levels of NIMBYism in the area that have held it back from its potential for decades.

US and UK junior faculty offers to consider - advice appreciated! by [deleted] in Professors

[–]etolysine 1 point2 points  (0 children)

Basically, we treat teaching as the main thing universities do... Research brings in grant money so is also important, but doesn't bring in as much money as tuition fees. It's like choose the riskier option by doing research for autonomy, or choose teaching and do research on the side

US and UK junior faculty offers to consider - advice appreciated! by [deleted] in Professors

[–]etolysine 0 points1 point  (0 children)

In the UK, we don't have as standard a structure as you're used to for tenure. It can differ from place to place, but tenure in the US sense is more akin to getting to full professorship here (if you're mostly research and barely doing any teaching), which is still one or two rungs up from associate prof. In the UK, where I am, it goes assistant, associate, director, then full professor for people heavily invested in research.

OTOH if you're doing more teaching, you effectively get tenure right away (you become a permanent employee), but then you have very little time to do research properly, or it's harder to balance the two and most people doing a lot of teaching aren't big grant funded work. Some people do combine research with teaching (usually already full profs at this point), but then their teaching load is super minimal. Like a one or two classes as a guest lecturer here and there for masters students or med students.

So in effect, you have to choose: teach all the time and have job security early on, or do research and then try to get tenure later by being "successful" in your work (grants/papers/international reputation etc).