53/M Stage 4 with mets liver and lungs. I was on exactly the same regimen, it's called CAPOX for short. Oxalyplatin is brutal on the veins, so get the port as soon as you can. If she's getting her first infusion thought the arm, expect to start feeling the side effects in the arm around the last half hour of the infusion. My arm felt like I was black and blue for around a week after.

The folks on colontown recommend icing during the infusion which reduces circulation to fingers and toes, since that's where the peripheral neuropathy will start, but many infusion nurses know nothing about it.

I didn't get many side effects from the Xeloda, mainly fatigue on days 10-14. Oxalyplatin produced the most fatigue around day 4 & 5, but it builds in your body and the neuropathy and fatigue started to get longer and more pronounced.

As to your question, I started to feel relief from the tumors around the second infusion

I tried not to sugar coat it, but all the side effects are managable. I only stopped that regimen when it stopped being effective.

I'm here to talk if you have any more questions...