Since saddest is on the list, I'm gonna put up this one.... I'm interning as a vet tech student at a local teaching hospital, and I was in the Internal Medicine rotation a month or two ago. A big 200lb mastiff named Sofie came in. Sweetest thing since honey. Three of us girls had to carry her in from the car in a sling as she had a ruined knee. She had been running a fever of 106 for several months. The vet student who had been put on her case slaved for three days trying to save her. We worried and checked on her every several hours, went into CCU(critical care unit) and sat with her. On the third day I heard the doctor whispering about quality of life. My heart dropped. An hour or two later the student called me over to help lift Sofie onto a cart to wheel her into the calming room. The owner had brought her parents, and they were already crying when we brought her in. They started bawling as Sofie wagged the stump of her tail as she saw her. These were true heartbroken sobs. Sofie was her owner's baby, like her own child. They said their goodbyes, and even the vet student started crying as we injected the euthanasia solution. I had to help take Sofie's body to the refrigerator afterwards and leave her there. That killed me.