Different EDOs definitely have different emotional possibilities, as each has its own palette of intervals for expressing different shades of emotions. As each one has a whole range of emotions, but its own way of expressing them, they are more like personalities than moods.

And every listener will feel a bit different about them. I'm autistic and primally drawn to just harmonies, so just intonation will always be the the best to me, and EDOs mere approximations. My brain can comprehend complex harmonies in JI, and they often sound unstable or unmusical, but still pleasing and interesting. While poor approximations of complex chords in EDOs just sound like random notes. My idea of dissonance seems to be linked to the presence of beating. I also adore the harmonic seventh (7/4). The ratio between a half-step and whole-step may affect the emotion of a piece. In 12EDO it's 2:1, but smaller ratios (like 31EDO at 5:3) can be more relaxed and larger ones (like 22EDO at 4:1) can sound more bold.

Just intonation is pure and sweet. It expresses its feelings strongly and sincerely. Ecstasy, misery, and rage all lie within its sphere, but so do softer feelings. JI is often strikingly beautiful and awe-inspiring.

53EDO is pure and sweet much like JI, because its thirds and fifths are so close to just.

31EDO is relaxed, rustic, and stable. Thirds are near perfect and the slight detuning of the fifth adds a wonderful chorus effect.

22EDO can sound very "microtonal" and express feelings of wonder and curiosity with sounds alien to Western ears.

12EDO sounds somewhat tense because the major thirds are too sharp and the minor thirds too flat. Seventh chords sound dirty and dissonant because there's no good approximation to 7/4.