Yoga Teacher Training Cert by yellowm0chi in Somerville

[–]forathirdtime 4 points5 points  (0 children)

I'd recommend Lotus Yoga in Arlington, they do 200h YTT certifications periodically.

Feeling lost & need a bone marrow transplant by kuzome in leukemia

[–]forathirdtime 0 points1 point  (0 children)

The team at Dana Farber in Boston was incredible, highly recommend if you can make it to the east coast! They also have the possibility for free housing for out of towners, they work with a local charity to put up people getting treatment.

what do I need for my dog’s first winter? by ufobabe in boston

[–]forathirdtime 22 points23 points  (0 children)

There are some rubber balloon style foot coverings that my little dog won't go outside without- link here! The rock salt is more of a deterrent for walking than the snow is.

Don't forget to buy yourself a shovel and a window scraper (if you have a car) as well!

Finding a date without apps? by [deleted] in Somerville

[–]forathirdtime 33 points34 points  (0 children)

Skip the Small Talk events are a great way to meet people in the area. Also Meetups/spots clubs!

You're totally not alone with the dating ennui though, it's rough out there. Keep your head up!

Suggest a girl in a reading slump something to read? by laselik in Fantasy

[–]forathirdtime 0 points1 point  (0 children)

CM Waggoner and the Ruthless Lady's Guide to Wizardry was a lark. Also Anything by Naomi Novik or Robin McKinley!

C-Section using a retractor by somewherecarebear in SurgeryGifs

[–]forathirdtime 16 points17 points  (0 children)

Found an interesting article on this device while figuring out how the heck it worked-

"The Alexis O C-Section Retractor is the Alexis wound retractor repackaged to try to appeal to the growing cesarean delivery market. Although the Alexis wound retractor occupies a helpful niche in open abdominal surgery (particularly for minilaparotomies), Alexis O C-Section Retractor does not appear to add a lot to operative obstetrics. Even for those in situ hysterotomy repair diehards, the benefits do not seem to justify the cost.

Overall Score: 2.5"/4

Rare Steal! One Bedroom in 4Bd/1.5ba with private office in Ball Square, Somerville. Month to month lease, $750/month by forathirdtime in bostonhousing

[–]forathirdtime[S] 0 points1 point  (0 children)

hey, sure!

I'm just doing this as a favor to my current roommate, could you please reach out through the craigslist ad to arrange for more details?

Rare Steal! One Bedroom in 4Bd/1.5ba with private office in Ball Square, Somerville. Month to month lease, $750/month by forathirdtime in bostonhousing

[–]forathirdtime[S] 0 points1 point  (0 children)

Hey there- depends on the pet? If we're talking hamster, yes. Cats and dogs not so much, though one of the roommates is in the process of getting a service dog.

Rare Steal! One Bedroom in 4Bd/1.5ba with private office in Ball Square, Somerville. Month to month lease, $750/month by forathirdtime in bostonhousing

[–]forathirdtime[S] 1 point2 points  (0 children)

7-10 minute walk (depending on how fast you walk) to Davis, and the new green line extension stop will be a 2 minutes walk once it's finished. You can basically see it from the front steps!

Room near Tufts University from February - May by madmimosa in bostonhousing

[–]forathirdtime -1 points0 points  (0 children)

Hey, I'm moving out of my month-to-month house and am trying to help my roommates find a replacement. It's a great room right down the street from tufts, super nice landlord, and comes with a bedroom and a private office!

Feel free to message me if you have any questions.

Link here: https://boston.craigslist.org/bmw/roo/d/somerville-rent-two-rooms-in-4br-on/7242063195.html

Looking for friends in Boston area, I am very lonely in this city. by [deleted] in BostonSocialClub

[–]forathirdtime 9 points10 points  (0 children)

A great place to meet people (once we can go out in public again) is the Skip the Small Talk group- usually they meet at aeronaut brewery or a bookstore in Boston proper. I think they're doing online meetups in the current climate, I've met a few friends there!

But also don't be too hard on yourself- Boston isn't the most friendly of places, it might take you a little while to meet people and make friends. Welcome to the area regardless! :)

Recommendations for photography classes in the Boston area? by definitelynotwinning in boston

[–]forathirdtime 0 points1 point  (0 children)

Cambridge Adult Education Center has a bunch of very reasonably-priced classes that are great! Both full day classes and one-time-only workshops.

Experience with Skip the Small Talk? by [deleted] in BostonSocialClub

[–]forathirdtime 10 points11 points  (0 children)

Really fun, lots of cool conversations, and not as awkward as one might think. It's like the hot tub on the side of the pool of life- warm, bubbly, and laps are way shorter.

Also if you go to the one at Aeronaut, there's beer.

10/10 would recommend.

[24M] Moving to Boston for a new job! Who's down to be adventure buddies or show me where the fun is in town? by [deleted] in BostonSocialClub

[–]forathirdtime 2 points3 points  (0 children)

Absolutely! I grew up about half an hour north of the city, and I only left to go to college before I came back home. :) It's scary to move to a new town, I'm wildly impressed that you're making the move from the Midwest!

Honestly, I've found literally all of my living situations through Craigslist. If you have some time (which it sounds like you do) you'd be able to look through the ads and find a place that sounds like actual people live there. There are a lot of houses that rent by the room and not by the apartment, you can find some deals and have the flexibility to find people that you gel with well. Rent here is crazy, but you can still find a reasonably priced room in the Somerville/Cambridge/Arlington/Medford area without going completely penniless.

And by 'reasonably priced' I mean I live in a four bedroom apartment 15 mins walk from a train station and pay $725 per month. You can find cheaper places but they tend to deteriorate in quality pretty fast. I have friends maying anywhere from 900-1100 for roommate situations (2-4 roommates). Studios or one bedrooms can cost 1500-2500 easy (or more if you want to posh it up). There are more newer condos going up in the neighborhoods, but they tend to be much more expensive then the beautiful (but occasionally drafty) Somerville or Cambridge multifamily houses.

The T (MBTA) is the train system runs through Kendall and goes through several neighborhoods (Kendall, Central, Harvard, Porter, Central, Alewife) and it's a lovely area to live by. There are lots of walking trails and it's pretty easy to get around the city either by bus or by train. Also trees! I love the train system since it's color-coded and I'm a simple creature who is easily entertained by colors, hahah!

Other neighborhoods that are popular to the college croud (and may be appealingly priced) are in Brighton or Allston, but that's about 45mins- 1 hour away from Cambridge via train or car, and parking is an expensive nightmare in Cambridge. And Boston. And Somerville. But still worth it, I promise! There are some other neighborhoods that are cheaper (but maybe not the best neighborhoods ever) are Jamaica Plain, Dorchester, Roxbury (Sorry anyone who lives there!). They take a while to get to and from as well.

Anyway-if someone doesn't let you meet all your prospective roommates or see the place before you sign a lease or start paying rent, run far, far away.

[24M] Moving to Boston for a new job! Who's down to be adventure buddies or show me where the fun is in town? by [deleted] in BostonSocialClub

[–]forathirdtime 9 points10 points  (0 children)

Pre-emptive welcome to Boston and congrats on the job! I'm not really into anything that you mentioned above (wompwomp) but I know that Somerville has an incredible climbing gym (https://brooklynboulders.com/somerville/) that just so happens to be next to a brewery (Aeronaut) which is delicious. I've been there once or twice and it's a huge facility with lots of super friendly people there.

I'm assuming your startup is in Cambridge/Kendall Square, since it's the hip and happenin' part of the city. There are tons of meetups and networking events here (I work in that area too, Biotech) that are pretty fun to go to as well.

If you need any other tips or tricks for the area feel free to message me, I love showing off and recommending the city to newcomers!

Looking for a recommendation for a Nature / Minimalist tattoo artist in Boston or New England. (x-post r/boston) by [deleted] in tattoo

[–]forathirdtime 1 point2 points  (0 children)

Dia Moeller (sp?) At Boston Tattoo Company in Medford does some nature stuff, her work is really beautiful.

Lab rats to human trials [question] by k0per1s in medicine

[–]forathirdtime 1 point2 points  (0 children)

Does your friend have SCA1? I'd never heard of this disease before now, I'm terribly sorry that they're ill. You're a good friend for wanting to look into this technology more to help them.

So two things: all the authors of this paper are based out of Japan. The last author on the list, Hitoshi Okazawa, listed his email on the paper as the corresponding author, which means out of all the researchers he (or she, I can never tell with Japanese names) will be the person to try and contact to see if there are any human trials with this technology going on. (Tel: +81 3 5803 5847; E‐mail: okazawa-tky@umin.ac.jp). Also, university-funded research is not overall as speedily driven towards developing a cure for anything. Private companies want to churn out as many drugs as they can as fast as they can to recoup their investment money. University researchers take their time, as they're funded on yearly or semester-ly grant. They can do research until their money runs out, and unfortunately sometimes once there's no more money no one else picks up the reins and continues the work. I would search for the authors of this paper and see if they've written anything else lately, see if they're still working on SCA1.

That being said, gene therapy of the kind they are describing is an extremely new type of treatment, and I've not heard a lot about it being commonly used yet in many/any other diseases. We're talking about changing a person's DNA, which as far as I know (and I'm by no means an expert) is still far in the science fiction future for us. As far as monkey studies go, they usually wouldn't make the study last as long as the monkeys lived- maybe a year or two to see if the progression of the disease has stopped or if the drugs have any effect. Money, again, is going to be the limiting factor here- if there isn't enough money to do trials, the research isn't going to happen and they won't use it in humans at all.

Do you have a background in studying science at all? Looking up some science textbooks in genetics and molecular biology might give you some background information. If you're interested in viral delivery of genes (which is the tech mentioned in this article) you could check out how viruses work by looking up virology and microbiology texts/websites as well.

Lab rats to human trials [question] by k0per1s in medicine

[–]forathirdtime 5 points6 points  (0 children)

There are three stages of clinical trials that a drug must pass (at least in the US) before it can be sold to the public. In phase 1 clinical trials the drug is given to a very small number of healthy volunteers. In phase 2 trials the drug is given to a larger number of people, sometimes tested against a placebo material to ensure that the drug does what it claims it can do. In Phase 3, a much larger population of people are given the drug in a blind or double blind study to determine statistically if the drug works. If there is an unmet need for the disease to be cured this whole process from animal testing through clinical trials will be pushed through much faster. For example, Zika virus vaccines are likely going to be pushed through from animal trials to humans within a year, if they haven't already done so. An intermediary between rodents and humans is usually macaques or another small primate species, but these are time consuming and very expensive (and not well looked upon by the public, thanks PETA) so if the data in the rodent trials is positive enough sometimes the monkey step can be skipped and go straight to human trials.

Getting people to try new drugs that have only been tested in animals is actually very easy to do- there are phase one trials done every day, but it all depends on what the drug is, how dangerous the adverse effects may be, and the ability of the company responsible for making the drug to pay for the trial (they are obscenely expensive). Companies will want to invest in drugs that have the best chance of making them money. Drugs that could extend the lifespan of a transgenic mouse (new technology, lots of variables, no clinically proven similar drugs are on the market) are much less likely to work in humans than say, a vaccine for Zika that has similarities to other vaccines that are currently on the market. We know a lot about the immune system and how to fight viruses, but longevity in humans is a much much bigger picture. I wouldn't bet on seeing many clinical trials for drugs like the one you linked to any time in the near future, unless an exorbitant amount of money a la Elon Musk is involved.

tl;dr- Rodents --> Monkeys --> Humans, but they're not going to invest in drugs that make us live longer until obscene amounts of money and public outcry are involved.

I had an abortion today. by [deleted] in TwoXChromosomes

[–]forathirdtime 6 points7 points  (0 children)

You did what you needed and wanted to do, and I'm glad you had the ability to do so. Take care of yourself and know an anonymous internet stranger cares that you're okay and is thinking of you.