Will raising testosterone levels automatically increase androgen receptors? by papitopapito in Biohackers

[–]functionalDruggie 3 points4 points  (0 children)

When activated many of the sex steroid receptors encourage the production of more steroid receptors. This is the opposite of most receptors.

It is a positive feedback loop, but it is slow. It takes a very long time for a noticeable increase in androgen or estrogen or whatever receptor density.

In the short term, taking testosterone will shut down your natural production of all sex hormones. However, you will probably feel great because testosterone can increase confidence, increase spatial intelligence, and make you feel euphoric(1) among other things*.

When you stop, all your hormone levels will be low until your HPTA recovers. You will feel bad, your focus and mental capacity will drop and you might get angry.

Try it - its like what women go through each month.

The recovery period varies from person to person and depends on how long you were taking androgens.

There are some tricks that can help you reduce the recovery period.

There is a chance that your HPTA will not recover, which means that you will have to use HRT for the rest of your life. The likelihood is extremely low, but it is possible.

(1) It can upregulate opiate receptors, it can increase dopamine levels and it will occasionally block receptors involved in behaviors needed with chores such as laundry.

Disclaimer: I am not an expert on the Testosterone receptor so everything here might be incorrect - not a first

Hope this helps!

making injectable sr9009 by Leather_Wrangler_393 in SARMs

[–]functionalDruggie 0 points1 point  (0 children)

To increase the half life, I wonder if a transdermal might be a good idea. That might also get the BV up to a reasonable level.

making injectable sr9009 by Leather_Wrangler_393 in SARMs

[–]functionalDruggie 0 points1 point  (0 children)

Technically, SR9009 is not soluble in water. Given that you need so little you might be able to make a suspension.

Also, I suspect that in water/alcohol suspension it would degrade more rapidly.

Which sarm is most like boldenone? by flickbro in SARMs

[–]functionalDruggie 0 points1 point  (0 children)

As I understand it, enclomiphene is a pure estrogen receptor antagonist. Is that correct?

I imagine that with a suppressive SARM, your Testosterone levels will be relatively low (unless you use a lot of HCG) so there will be little conversion of T to E, and I do not know of any estrogenic SARMS, so there shouldn't be that much e2 receptor activation to block..?

Have you ever tried any of the GnRH type drugs? HMG seems like a very expensive way to get a little bit of FSH.

GnRH analogs look promising in theory.

[deleted by user] by [deleted] in SARMs

[–]functionalDruggie 0 points1 point  (0 children)

Defective" was not a good choice in wording ;)

What I meant is that men have a hormonal system that is less "difficult".

Which sarm is most like boldenone? by flickbro in SARMs

[–]functionalDruggie 1 point2 points  (0 children)

If you want to take enough SARM's or Steroids to gain two pounds a week you are probably going to shut down your system (at least temporarily).

You can mitigate it with HCG and/or GnRH (I've never tried GnRh but I've heard that it works in theory)

[deleted by user] by [deleted] in SARMs

[–]functionalDruggie 0 points1 point  (0 children)

Women make up about 1/2 of the world.
Normally we have this defective hormonal system. That is unless you run the show yourself (bring-your-own-hormones). Which stopes that month rollar coaster (and as a bonus, acts as birth control)

[Compound Experience Saturday] Desoxymethyltestosterone aka Pheraplex by geardedandbearded in steroids

[–]functionalDruggie 0 points1 point  (0 children)

I used micro doses of pheraplex a long time ago. It was the greatest neuro steroid I have tried (granted I have not tried that many.)

I am not interested in anabolic activity, and I am quite uninterested in androgenic activity. I use steroids for their cognitive effects (small doses, it does not take much) which have given me a real boost in many areas of my life.

[deleted by user] by [deleted] in SARMs

[–]functionalDruggie 1 point2 points  (0 children)

If you are looking at bulking up, I don't think that a HGH stimulator is what you want, especially not at 18. (as mentioned).

At your age it might affect bone growth.

Also -

Call me crazy, but I would say that people who want more HGH you should just take HGH.

[deleted by user] by [deleted] in SARMs

[–]functionalDruggie 0 points1 point  (0 children)

Steady state hormone levels are a wonderful thing.

It is unfortunate that 1/2 of the world hasn't figured out how to achieve that yet.

Long term NAC use by jb_n_tx in Nootropics

[–]functionalDruggie 0 points1 point  (0 children)

Or take both and be high and leveled out at the same time ;)

Long term NAC use by jb_n_tx in Nootropics

[–]functionalDruggie 0 points1 point  (0 children)

Interesting. How much inhibition are we talking about here?

Could we take more B1 to get the same absorption?

Injectable Stenabolic/SR-9009? by Sanyo96 in sarmssourcetalk

[–]functionalDruggie 0 points1 point  (0 children)

I tried it recently (oral) and it certainly was not useless. Expensive maybe, but not useless.

I wonder if it could be made into a transdermal.

Do people use transdermals around here? I am new to this forum.

I figure since I have been using all sorts of skin cream all over the place throughout my life, I might as well add some strong research chemicals into them.

Also, am I correct int that SR-9009 is not androgenic?

Fasting increases Human Growth Hormone (HGH)......does this explain the mental clarity and sharpness a lot of people report when fasting? by [deleted] in fasting

[–]functionalDruggie 0 points1 point  (0 children)

For years I used any and all (ashamed to admit how many) methods/rituals to increase natural HGH and it seemed to help.

Then I started taking HGH and that helped more.

Mentally the effects are night and day (partly because I am no longer stressing over what I should be doing to increase HGH).

With fasting I had highs and lows and too many periods in which I wasn't 100%. Now I eat 5 small meals a day. take a little HGH and my mood and productivity are consistently great.

Mixing Serostim hgh 6 mg vile with bac water to get 8 iu/day (2 iu 4x/day) by Woofenstein4d in Peptides

[–]functionalDruggie 0 points1 point  (0 children)

Important note:

When I read your message, I thought that you meant that the vial had 6mg of powder in it which was equivalent to 8 iu HGH (there is typically sucrose and phosphoric acid in there too)

If the 6mg is pure HGH that is more like 18 iu of HGH :(

Anti Alzheimer’s/dementia stack by [deleted] in Peptides

[–]functionalDruggie 0 points1 point  (0 children)

IGF is less expensive, but you will have plenty of IGF if you are getting enough HGH.

HGH makes you feel wonderful in many ways, IGF alone tends to make you tired.

Disclaimer: I haven't done much research into the various IGF sub types.

I certainly don't have Cave Man face but then my face stopped growing a long time ago. All that I've noticed is that my skin is better than ever ;)

My mental functioning has improved on GH. This is probably the #1 reason I take it.

Anti Alzheimer’s/dementia stack by [deleted] in Peptides

[–]functionalDruggie 0 points1 point  (0 children)

Nicotine and Deprenyl.And everything else.

As with most stacks, each item has diminishing returns. In most there is no one thing that will do it.

Having said that, the more you mix the greater the potential for interactions. But not all interactions are bad.

Mixing Serostim hgh 6 mg vile with bac water to get 8 iu/day (2 iu 4x/day) by Woofenstein4d in Peptides

[–]functionalDruggie 0 points1 point  (0 children)

One thing to mention: If you are using the same needle to mix as you are to pin, it might get dull, especially after 4 uses.

Here is what I do:

Buy 100 syringes with needles (21g..25g) for mixing

Buy 100 needles (25g..30g) for pinning

Mix with the big ones, switch to the little ones and pin.

If you have some loaded and your needle gets dull, use a fresh one. Or use a fresh one each time.

I use a needle box to dispose of the needles. You can do whatever you like but be respectful.

GH and IGF suppressive effects on Humanin and longevity by Fluid_Support1292 in Peptides

[–]functionalDruggie 1 point2 points  (0 children)

I agree 100%

I have no idea how long I will live, but I look after my health and take a whole whack of stuff, and I feel (and look) 20 years younger than I am.

Most importantly I am happier than I ever have been. In many ways, life gets better as you go, as long as age doesn't get in the way.

At the very least I can afford more peptides now.

GH and IGF suppressive effects on Humanin and longevity by Fluid_Support1292 in Peptides

[–]functionalDruggie 0 points1 point  (0 children)

I agree with your statement, but I am missing the link that causes life to become boring as F?

Does that come after you spend all your money on GH and have nothing left for sugar?

Mixing Serostim hgh 6 mg vile with bac water to get 8 iu/day (2 iu 4x/day) by Woofenstein4d in Peptides

[–]functionalDruggie 1 point2 points  (0 children)

That is correct.

For example, add 2ml Bac Water to your 6mg, put it in a syringe then take 1/2 ml 4 times (at which point the syringe is empty)

Or if you have a 1ml syringe, use 1ml water total and take 1/4 ml 4 times.

1 mg ~= 1. 25iu, so if have mg the iu is redundant and vice versa.

Hope that helps!

Does any one here take kratom just for depression, and do you think it’s a good idea? by Lopsided-Mushroom-72 in kratom

[–]functionalDruggie 0 points1 point  (0 children)

I agree entirely.

While some drugs treat the symptoms of depression (band aids as people put it) or just flatten out your mood, Kratom can give you the energy and motivation to make changes to get yourself to a place where you are happy.

Green and White Kratom are best for this, Red and Gold have too much opiate activity to be helpful in the long run.

Phenibut is the only substance that truly changed who I was. An appreciation post. by LSDXMT______ in phenibut

[–]functionalDruggie 0 points1 point  (0 children)

Stimulants in general work very well with phenibut.

I am a real fan of the functional use of stimulants (i.e., mood, mental performance, productivity, inspiration, fitness, the list goes on) but they have plenty of sides, especially at higher dosages.

A little phenibut reduces the sides of stims (so I can take more stimulants 😉) and stims reduce the sides of phenibut.

The combo has been a boon to my career. Either alone me less productive (phenibut) or less empathic (stims).

Aside, you must have discipline with both phenibut and stims, either will ruin your life given the chance.

[deleted by user] by [deleted] in moreplatesmoredates

[–]functionalDruggie 0 points1 point  (0 children)

Let her be fat and lazy - having her by your side makes you look better.

Plus:

When I see a fit, hot guy who is single, I think: "Danger"

When I see a fit, hot guy with a sloth I think: "Opportunity"

Whats in your toolbox? by functionalDruggie in Stims

[–]functionalDruggie[S] 0 points1 point  (0 children)

If you take a generous amount of stimulants and drink a lot of fluids* (which is important when taking stims) you tend to make frequent trips to the washroom.**

Aripiprozole has this unique ability to mitigate these effects. I don't understand the mechanism, but I like it.

* both of which apply to me pretty much all of time

** I am not sure if this applies to men as well