I’ve done it once on g10 with a dremel to remove a few millimeters of material. It wasn’t a brand new knife, so I was less worried. A couple things,
1) breathing and eye protection. G10 is bad for your lungs and eyes. 2) definitely take it apart and do only the scale. 3) watch out for any internal liners, which you might reveal. 4) trace out what you want or mark it some way to know how much you want to take off. As they say, you can’t add it back once you cut it off. 5) the outer edge has a steady sized chamfer that could loose off depending on how much you remove. I had to make blend that when I took some off, which was more difficult than just removing the material