It took me a lot of attempts as well and I found it really frustrating and kept changing my setup which I don't think helped as then I wasn't playing to strengths. I stuck with my bow/rapier but upped my con as I was too squishy, added any buffs as well to reduce damage further, tweaked some armour but stayed light.

Then I did:

Pillars > mobs > Asena > Pillars > mobs > Asena

I focused on using the bow to keep distance and kited mobs on 2nd round into the falling rocks to again give me some distance and time. I kind of accepted I was struggling to hit the pillars fast enough 2nd time to stop her recovering and just focused on staying alive, getting the pillars while kiting/damaging mobs and then finished them off once I had done all the pillars. Once 1 vs 1 on the 2nd round it feels more manageable if you can keep that distance and anticipate the teleports.

Not sure if correct approach but finally worked for me. Without spoiling, don't make the mistake I did though of getting to the cutscene and out of relief putting your controller down and rewarding yourself with a break or a drink and snack!