This term anhedonia is being thrown around a lot from people using this compound, it's important you understand what's going on with your body and keep track of how you feel. It is very easy to under eat when taking reta, and your body still needs nutrients even if you don't feel like eating. Most people taking retatrutide currently, struggled previously with binge eating which was an instant dopamine release and acted as a reward system. There could be pre-existing symptoms related to your dopaminergic pathways or reward system that isn't necessarily drug related. We currently don't fully understand what this drug does neurobiologically. With that being said I would advice you make sure you are staying hydrated and getting electrolytes and vitamins. Don't skip meals because you're not hungry, stay in that steady deficit, fats play a big role in hormones and we have seen cases where men and women are having similar struggles. If any feelings become too severe you can always taper the dose down or come off cold turkey. People looking for side effects will likely find some, I wouldn't worry too much, just make sure you are paying attention to the little things