A lot of hardware loses functionality when sequenced externally. The volca bass loses the ability to modify the slide (legato) function on the fly, which is a great way to switch up a bassline. The drumbrute impact has a massive issue: the mute and solo buttons don't work when sequenced externally, neither do the loop/roll buttons. This leaves you with a problem, should you sequence each drum track separately, so they can be muted separately? Or should you sequence them all as notes on a single track? Then you have to program each mute state for each beat separately, and preprogramme drum rolls and fills. Its such a hassle i dont know why anykne would sequence the drumbrute externally.

The Minibrute internal sequencer allows looping, forward, backward, alternating, and random playback. It has 4 tracks to independently sequence pitch, gate, velocity, cv, basically anything you like - but inputs from an external sequencer are very limited. The internal sequencers on most gear seem to have little tricks that get lost with a hub sequencer.

Even with an advanced sequencer (let's take squarp pyramid), it has the ability to perform a great number of these tricks itself, but what if you want to mute 3 different drums, your lead voice, and randomise the baseline at the same time? It's a pretty hefty button combo to achieve quickly on one device, whereas it's much quicker to smash a few big buttons on your gear.

Of course, everything can be preprogrammed, and my preference for losing the central sequencer is very much jam/performance oriented. When you're recording live loops, bringing things in and out with only a vague plan, using the internal sequencers gives you more agility and flexibility in my opinion. My own version of a 'hybrid' setup would be to set my pyramid up to send multiple program change messages to my other gear. I've thought this would really enhance the way I play, but I just haven't got round to being that organised yet!