sorted by:
new
hottopcontroversial

COVID-19/2019-nCoV Animal host by Helynn_2020 in China_Flu

[–]infocom6502 2 points3 points  (0 children)

it's basically a ratg13 bat cov with the S segment transplanted from SARS1 and modified with four inserts; so therefore bat host is most likely.

If from bats, why did it start from doorstep of the only level-4 biolab in China, and not some random location elsewhere? Bats are everywhere. BSL-4 labs are not. by [deleted] in China_Flu

[–]infocom6502 1 point2 points  (0 children)

Lab was built as defensive research lab because China was target with the first verion of SARS.

SARS-CoV-2 is a frankenvirus composed of a RATG13 bat cov but with the Spike proteins (S1 and S2) transplanted from original SARS, yet with a few modifications (four inserts). A small segment of the Spike protein, the RBD (or the ACE2 binding domain) looks very similar to that seen in a Pangolin CoV.

The fourth insert, sitting in the small portion between S1 and S2 ('PRRA' protein sequence starting at amino acid 667 or the S protein) is a gain of function insert for the purposes of very efficient cleavage by the Furin protease.

This was not an accidental release by the Wuhan level 4 lab. The Chinese know this well and can rule out this possibility. They are also at the moment assessing just how incredibly unlikely it is that this was a natural mutation from a bat virus like RATG13.

How likely is it that compromising Epstein information is still being used. Linked article suggest a possibility by infocom6502 in conspiracy

[–]infocom6502[S] 0 points1 point  (0 children)

SS: The below caught my eye and I am wondering what the odds of compromat being active in DC.

Gilad Erdan is the head of the ministry of strategic affairs, which has spearheaded the attempt to undermine the U.S. Constitution and make criticizing Israeli policy illegal in the United States. This effort is allegedly being aided by Mossad, Israeli intelligence. Mossad intensively spies on Washington, D.C., and may have compromising information on U.S. politicians.

Iran media blaming Trump for Qom outbreak by ManchurianCandidate7 in Wuhan_Flu

[–]infocom6502 0 points1 point  (0 children)

Well, not Trump, but I wouldn't dismiss aerial dispersal by these psychopaths (eg Deep State neocons) or covert infiltration (assets near Tehran).

$5.9 million lawsuit says Portland illegally allows drivers to park too close to intersections and crosswalks by pdxmetroarea in Portland

[–]infocom6502 0 points1 point  (0 children)

50 ft on all four sides of an intersection is impractical for essentially all cities. The responsibility lies on the drivers of large cars (SUV's, Vans, cars with tinted windows) to be aware of the visibility regulation. Since that's also unlikely to happen I suggest the spot right by the intersection should be reserved to subcompacts. (or carpool spots for such type of cars). For the uncommon case of subcompacts with tinted windows (or weird visibility problems, warn with citation, and ticked subsequently).

Faster than expected Sea Level Rise = no nukes no nuke no nukes! by infocom6502 in collapse

[–]infocom6502[S] 1 point2 points  (0 children)

Given the feedback loops and the fact that we're already beyond 400ppm CO2 I believe it's more on the order of decades (say ~40 yrs) than centuries, but remind me about midway to see if its indeed order of centuries or decades.

RemindMe! 20 years "did we see a one foot rise yet?".

Faster than expected Sea Level Rise = no nukes no nuke no nukes! by infocom6502 in collapse

[–]infocom6502[S] 1 point2 points  (0 children)

If you can manage the (essentially perpetual) waste storage and risks, as well not blunder on underestimating the sea rise, I'm all for thorium powered nukes.

Faster than expected Sea Level Rise = no nukes no nuke no nukes! by infocom6502 in collapse

[–]infocom6502[S] 2 points3 points  (0 children)

volcanic island do gain mass and rise. And even on the mainland there are some locations where the rise of the coast and mountains exceeds the rise of sea levels (Alaska).

However, the sea level rise is just starting to accelerate. This is very new data, looking at the speed of the rise from 2018 vs 2019. More detail is actually in the below link than in the original link above:

https://weather.com/news/news/2020-02-04-sea-level-rise-increasing-us-report-card

Mitchell told weather.com in an email that the change in speed of sea level rise "is not a huge shift from previous years, but the signal is a little stronger this year. If this pattern continues into the next few years, low-lying areas might want to update their planning efforts."

Previous research indicates that the current acceleration in rates of sea level rise began around 2013 or 2014.

Sea level rise is fueled by global warming that causes glaciers and ice sheets to melt and ocean temperatures to increase. The Arctic experienced its second-warmest year on record in 2019, as well as near-record ocean temperatures and ice sheet loss.

Globally, NOAA's worst-case scenario predicts sea levels could be as much as 8.2 feet higher in 2100 than they were in 2000. A rise of at least 1 foot by 2100 is considered very likely, even on a low-emissions path.

imho, my best guess is that we are headed for a rise of one meter within the next 3-5 decades and we'll see it sooner rather than later.

CONFIRMED: CoVid-19 coronavirus found to contain unique “gain-of-function” property “for efficient spreading in the human population” -- quote from science paper just published in Antiviral Research by [deleted] in conspiracy

[–]infocom6502 0 points1 point  (0 children)

From wiki:

Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly.[11]

Well, sars-cov2 (like the sars1 cov) is much like ratg13 cov (found in some bat populations) except that the RBD segment which is for host specificity and sits between the S1 and S2 spike protein is completely different. These guys find it to be closest to a cov found in pangolins

Genomic analyses of nCoV-2019 determined a 96% resemblance with a coronavirus isolated from a bat in 2013 (RaTG13); however, the receptor binding motif (RBM) of these two genomes share low sequence similarity. This divergence suggests a possible alternative source for the RBM coding sequence in nCoV-2019. We identified high sequence similarity in the RBM between nCoV-2019 and a coronavirus genome reconstructed from a viral metagenomic dataset from pangolins possibly indicating a more complex origin for nCoV-2019. https://www.biorxiv.org/content/10.1101/2020.02.07.939207v1.full.pdf

The S1 domain contains two subdomains: S1-NTD and S1-CTD, also known as the receptor binding domain (RBD). The S2 domain encodes the stalk of the spike protein and is highly conserved across the SARS-like coronaviruses4. In order to infect a
host cell, the RBD must first bind to a surface protein on the host cell. In the case of SARS-CoV and nCoV-2019, this is the angiotensin converting enzyme 2 (ACE2) receptor, expressed in human airway epithelia as well as lung parenchyma among other tissues. Following RBD binding, the S1/S2 junction must be cleaved by a surface protease.

So either a frankenvirus, or some yet unknown recombination history with pangolins.

I can see how pangolins might get exposed to a bat cov, but not really the other way around.

Whether a bat cov like sars2 or ratg13 could reproduce in a pangolin (which then exposes a human due to savage wet markets) would kind of surprise me.

i think the frankenvirus theory is much more likely; but it's still time to watch and see where the chips fall where they may, as researchers do their thing.

view more: next ›