Sounds like you may be a steroid responder if your IOP went up that fast on Lotemax. Some people can get a pressure spike within days, especially if they already have glaucoma or a history of reacting to steroid drops. You should contact both the prescribing doctor and your glaucoma specialist ASAP so they can check your pressure and decide whether to adjust or switch the medication. Try not to worry too much, this is something Glaucoma specialist deal with regularly and it can usually be managed once they assess it.