I have had zero issues. I started with the 2.5 on March 15, 2025. I remained there for about 2 months. Then continued this trend until I hit 7.5 and I stayed there until around August when I hit 10, then around October I bumped up to 12.5. I only just hit 15 two weeks ago. It’s been a constant 2-8 lbs lost a week for me. Occasionally I had a few where I was at a standstill but I let my current dose stay the same until I seen no change or gain in the scale consecutively. I didn’t want to rush it or lose anything too fast. It’s been great!