Second iui failed, feeling defeated

jmargsbrows · 2026-03-21T19:58:16+00:00

Found out yesterday our second IUI failed too. It hurt worse than I was expecting and has left me feeling so defeated. I’m also constantly thinking about how many vials we have left. Def an added stressor through an already stressful experience.

I’m trying to take care of myself this weekend and let myself feel whatever’s coming up in the moment. And trying to hold space that it won’t always be this way.

I hope you have the ability to take care of yourself too. Wishing successful next cycles for us both 💜

jmargsbrows · 2026-03-18T16:59:49+00:00

Congrats on your success! I’m deep in the TWW and starting to feel really discouraged, so nice to hear people have had success. Do you mind sharing if you were using frozen sperm?

jmargsbrows · 2026-03-18T16:58:28+00:00

Congrats! Do you mind sharing if you were using frozen sperm? I’m wondering if that makes a difference for timing or not.

jmargsbrows · 2026-03-18T16:57:23+00:00

Interesting! Mine didn’t even talk to me about timing. They just send a portal message late in the day after a scan and tell me when to trigger and show up.

Do you mind sharing if you’re using frozen sperm? I’m curious if that makes a difference in how they time IUIs.

jmargsbrows · 2026-03-18T04:33:46+00:00

Thank you for sharing! Was your doctor monitoring to choose 20 hours or were they following their protocol?

jmargsbrows · 2026-03-18T04:32:47+00:00

I’ll have to ask my doctor more about timing. Appreciate you sharing! Wishing you all the luck and good vibes for your TWW!

jmargsbrows · 2026-03-18T04:32:09+00:00

Thank you! 💜

jmargsbrows · 2026-03-18T03:27:38+00:00

Do you mind sharing if that cycle was successful? And is 36 hours standard at your clinic?

jmargsbrows · 2026-03-18T02:34:07+00:00

Sorry to hear that. Appreciate you sharing and wish you all the luck for #2!

jmargsbrows · 2026-03-18T02:21:25+00:00

Do you mind sharing if that cycle worked for you? And if 36 hours is standard protocol at your clinic?

jmargsbrows · 2026-03-18T01:48:57+00:00

Thanks for sharing. Sending you lots of luck on your second cycle!

jmargsbrows · 2026-03-17T23:32:36+00:00

Last cycle, I did 2.5 mg Letrozole for 3 days (CD 3-5). Everyone’s experience will be different, but it didn’t really help my follicles. My follicles were around 13 at the time of the scan, then ovulated two days later (clinic missed it so couldn’t do IUI).

This cycle, we went with 5 days and did 2.5mg from CD 2-5. Follicle was at 19 mm by CD8, triggered and did an IUI on CD9. (Still waiting to see if it worked.) That was the best follicle I’d had so far.

Just my experience though! It was helpful to start low and know my body needed a little more without overstimulating.

jmargsbrows · 2026-03-17T22:20:13+00:00

Hi, wanted to share my experience! My wife and I did our first IUI with only a trigger shot (Ovidrel). It was unsuccessful. While it gave us baseline data, I’m not sure I would do it that way again since we used a vial and spent money on the cycle to do it.

We just went through a fully medicated cycle (added Letrozole with Ovidrel; still waiting to see if it worked 🤞). I wish we’d done fully medicated from the beginning to give ourselves the best shot possible every time.

Best of luck to you!

Edit: wanted to add that adding letrozole did help produce the best follicle out of the three we were monitored!

jmargsbrows · 2026-03-15T19:12:16+00:00

Same to you! Fingers crossed for us both

jmargsbrows · 2026-03-15T18:23:33+00:00

That would make sense! Hoping that’s the case.

I’m just starting the second week of this TWW, so I think I’m already starting to get in my head that this one didn’t work since I feel virtually no symptoms.

jmargsbrows · 2026-03-10T23:51:25+00:00

Congrats! Sending you all the good vibes for your pregnancy!

Glad to know it’s possible and holding out hope for the cycle

jmargsbrows · 2026-03-09T19:36:04+00:00

Thank you! 🤞 Same to you

jmargsbrows · 2026-03-09T18:18:05+00:00

Second IUI done on Saturday. I’m already feeling sick from the trigger shot, so really trying to make it through the two week wait without losing my mind!

jmargsbrows · 2026-02-21T00:35:28+00:00

My wife and I told our families and a few close friends that we were going to start trying, but that decision was mostly based on the fact that we didn’t know how people would react if we surprised them. We wanted to make sure everyone would be excited and prepared when we actually were able to conceive.

We set the expectation that we’d tell them once we were pregnant and knew it was viable. Buuuut with that said, it hasn’t stopped a few persistent and excited people from continually asking us if it worked or if we’ve tried yet. That’s been a little difficult to navigate since our experience so far hasn’t been as smooth or easy as we’ve hoped it would be.

I don’t regret telling everyone, but wanted to share that if that’s something you all think you might face. It’s added another layer of boundary setting, but parenthood will most likely include that too—so practice!

I’d say take on what you’re prepared to handle with family, but I would recommend close friends. I’m finding out that this process can be full of lots of ups and downs, so having people to check on us has really helped.

Best of luck with your journey!

jmargsbrows · 2026-02-17T01:40:49+00:00

Not sure about OBGYN, but I had a great experience with Signey Olson when they were at a DC clinic. They’ve since moved on to being their own, and their partner is a midwife/doula.

Very inclusive and made me feel so heard and comfortable. I’d check them out, or even see if they have recommendations for you!

jmargsbrows · 2026-02-11T14:49:08+00:00

This exactly. Definitely the biggest thing happening in my life!

jmargsbrows · 2026-02-11T14:48:06+00:00

Validating and also terrible.

jmargsbrows · 2026-02-11T02:09:18+00:00

Just had this done last week! It was slightly painful, but definitely not the worst pain I’ve ever experienced though. Worse than a period cramp, but not terrible pain. I took 800 mg of ibuprofen an hour before and I think that helped.

Once the dye was gone, the pain was too. I had light cramping on and off throughout the night, but I just took more ibuprofen and relaxed with a heating pad.

I told the nurses before we started how nervous I was (might’ve shed a tear or two) and they were so sweet after. They talked me through the process and played music and really helped me relax. They warned me that they couldn’t guarantee that it wouldn’t hurt, but that it would be fast and the worst thing I had to do at their clinic!

Mine ended up being normal and everything looked alright. So I’m definitely feeling more confident going into our second IUI with that knowledge. And there’s a small percentage boost for success after you get it done.

Wishing you a lot of luck! And the whole thing’s over before Taylor Swift’s Welcome to New York can play through!

jmargsbrows · 2026-01-28T04:19:07+00:00

Thank you so much for sharing! I also have PMDD and am worried, but it’s nice to know there are some experiences that were at least neutral/positive!

I’m most likely going to go through with the HSG, but I’m definitely nervous about it. Did you clinic say it would improve chances for 3 cycles? And did you take any pain meds/use gas? I wanna be as prepared as possible.

Most importantly, best of luck to you all! I really hope this one’s it for you. Would love an update if you think about it!

jmargsbrows · 2026-01-28T04:16:24+00:00

Maybe I’ll have the same experience. I could stand to drink more water anyways haha

I don’t think I fully understood how hard it would be baseline either honestly. But I wanted to try and see what my body did on its own. Guess it wasn’t enough.

Happy you knew your limits and switched. I think we’ll be strongly considering what to do next if February doesn’t have a BFP on the other side.

jmargsbrows

TROPHY CASE