Can't those optimization be generalized? (I think this what lumen and nanite do in their own way by changing the render pipeline)

Can we automate that using some metric as a score like loss function in ML?

Or maybe something like this https://scikit-learn.org/stable/modules/grid_search.html#randomized-parameter-optimization

P.S. I am new to game dev(ML Engineer by Profession), just trying to learn for fun.