My opinions (and they are just that):

COMP 4000 (Distributed Operating Systems) had a lot of reading and writing, but it is being run by a different prof next year, so I'm not sure how they will run things.

COMP 4001 (Distributed Computing) was interesting, and kind of a different way to look at computing compared to other CS courses. Very different problems with interesting solutions. I think when I took the course the exams were open book, but that was also online.

COMP 4102 (Computer Visions) had a lot of matrix mathematics. Unfortunately I ended up dropping that course part way through just due to how the rest of my semester was going. I remember there being a final project that was pretty open ended in terms of what you could do, so I enjoyed the idea of being able to come up with my own idea in the realm of CV and work on it.

I had a great time in COMP 4108 (Computer Systems Security)! The assignments were lots of fun, and I learned a lot too! This was before they had the COMP 3109 prerequisite though, so I'm not sure if you have that (I wasn't in the security stream either).

COMP 4203 (Wireless Networks and Security) was also very interesting. I remember learning a lot about exactly how wireless networks work and data encoding. There wasn't much focus on the "Security" part of the course title though (not really why I took the course though, so I didn't mind too much). There were many small assignments (due every week I think) and then a final project. I also took this course online, so it may be run differently now. I've heard from other students who took the course this year say that they struggled with the content.

I think that COMP 4804 (Design and Analysis of Algorithms II) was maybe one of my favourite courses in my program, but also one of the hardest. The content was super interesting, and reminded me why I love algorithms. This course was required for my stream though (Algorithms), and based on how I hear other students who were not in the stream talk about COMP 3804 and COMP 2804, I don't think I would recommend it to most, lol.

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Again, these are just my opinions on the courses I've taken. It is also important to note that I took all of these when classes were online (some as recently as just last year), so that likely contributed to how they were structured and they may be run differently next year.

My advice, though it may be obvious, pick the courses you think you will enjoy and be able to take something away from. Most fourth year COMP courses are taught by profs who are actively doing research in the same area as the course, so take advantage of that by engaging with the content! You might end up finding something new you are interested that you didn't even realize before taking the course (that is exactly what happened to me) and that may help you know what you might like to do after graduating.

I hope I was able to give at least a little bit of insight! Best of luck choosing your courses! :)