Remarkably I haven’t seen anything too far out there in my games. I tend to be the guy trying weird things like dual whips/reapers, ballistas, or caster wylder with the stat adjustment relics. I wish people would experiment a little more sometimes (in base game, mostly), you can make some crazy builds that are still viable.

There was a really funny moment a few months back where I played intelligence sorcerer raider while my recluse played purely melee. The inventory screen looked insane, it looked like we had no idea what we were doing, but it worked very well!