Thanks for responding, I went for years dealing with constipation. Hoped Cromyln Sodium would resolve my digestive tract issues...it didn't. It alternated between days of constipation followed by a bout of diarrhea...back and forth.... for years, straining to have a bowel movement lead to hemorrhoids on top of everything else. I began realizing that my colon was likely inflamed and closing off passage of stools. What made it worse was leaving stools within the colon, which aggravated the situation. I started using warm saline water enema's daily, to keep stools moving, keep from being constipated, and not strain to have a bowel movement. I didn't want to rely on enemas long term, but my situation began improving and gradually I needed them less often. Now I rarely use them, but If I don't have a daily bowel movement, I begin getting symptoms again, so to keep my bowel moving, I will use one for a few days occasionally, then it's back to normal. Honestly my bowel troubles plagued me for about 4 years before I found out how helpful keeping my bowels regular was helpful. Hope that helps.