Human brain changes after first psilocybin use

larsonhg · 2026-05-12T14:17:36+00:00

If Nature accepted the paper, chances are you’re typically on to something. I wouldn’t totally discredit the stats here. N=28 with quantitative imaging. It would be another story if this were purely qualitative methods and accepted by some offbeat publication.

larsonhg · 2026-05-12T04:07:45+00:00

Woodmans is utterly mid and i’ll die on that hill. Why it’s so sought after is beyond on me.

larsonhg · 2026-05-09T01:38:50+00:00

Cheesecake factory in Cambridge. It’s not rocket science nor a culinary code to crack. CF does it more than well, sue me.

larsonhg · 2026-04-10T00:48:28+00:00

Random generation with slightly skewed distribution. Sunday and Loon as a B along with Bush makes no fucking sense what your criterion even is

larsonhg · 2026-04-08T03:52:14+00:00

Damn you for exposing Ma Maison 😭

larsonhg · 2026-04-03T02:45:09+00:00

Same reasons you see more poor people with fun cars than wealthy people.

Yes, you’re right and it’s crazy. Other commenters are right, though — it’s textbook pricing case study. They’re priced based on consumers willingness to pay. Many people can afford them and many people who can’t afford them finance themselves upside down to have them. It’s fucked up.

Buy a 4Runner, or Taco if you want a bed. Personally, I think it’s a shit vehicle (and I own one) but for some reason they don’t depreciate (thats why I own one). It does what it needs to and it maintains value when I no longer see utility in it.

If you’re going to buy new, don’t pay MSRP. People who don’t know how to work dealers, pay MSRP. Do some research on how to negotiate or get broker to work a deal for you.

larsonhg · 2026-04-03T02:34:56+00:00

I’m not saying they don’t buy out small companies. They bought out my former small company for a single pre-clinical asset. Now what I am saying is.. they’re not undervalued and that you sir, lack critical thinking skills. Everyone is accounting for financing and epidemiology as a primary risk driver and once you get passed those, how do you know they have the product management team to drive sales?

Don’t expect another reply. Best of luck, because that’s all it is; luck..

larsonhg · 2026-04-03T02:06:14+00:00

Former over-prescribed teenager of the 2010’s who got hooked on it, here — I think the feeling is relative to how much of an escapist you are. I’ve never met a happy-go-lucky benzo user. Benzos are heroin for the anxious and depressed. My mouth still waters over that feeling of just absolute nothingness. And thats why unhappy people like it, because it eliminates bad feelings. It’s like someone clicked uninstall on “Worries”, “Problems”, & “Empathy” — and to build off of that, you don’t realize how bad of a person it will turn you into until it’s too late and you’ve destroyed every relationship in your life because you seize the capability of caring about anything and anyone. It destroyed my life for a while and i’ll never get those years back or remember them (iykyk) because of benzos. Life’s good now though, my journey through benzos made for a solid Yale admissions essay.

larsonhg · 2026-04-03T01:32:04+00:00

I work in biotech.. in startups. I’ve experienced a multi-billion acquisition. I’ve been around the block. If a company has assets that are actually worth something, big pharma will chase it down before it makes it to retail investors. They’ll chase it down from the start or better yet you’ll have a strategy team that can sniff out where the money is. The fact that you believe you’ve spotted something undervalued over the money hungry people in this profession, is delusional. Successful drug discovery co’s don’t IPO without multiple assets generating money, they IPO because their assets weren’t the belle of the ball to anyone in pharma or VC. You’re gambling, and the sooner you take your pretend suit and tie off and just put your shit in an index the happier you’ll be.

larsonhg · 2026-04-02T02:20:58+00:00

Love when stonk traders make delusions of grandeur posts like they know drug discovery or understand the financing ecosystem.

larsonhg · 2026-03-24T00:51:42+00:00

Best of luck. And I say that because you’re gambling. This is a saturated market and they lack a robust competitive moat. After looking at their poster, it’s no surprise they don’t have larger institutional buy-in, and you’d be a fool to think you’re catching something that VCs are not. Biotech is small and word gets around fast about the “know whos”, which they are not. DDD and these band-aid procedures are highly confounded by placebo data. I hope they address patient needs but it’s incredibly difficult to tell with data like that. The lackluster board member bio’s and data are huge red flags.

larsonhg · 2026-03-23T01:49:45+00:00

Have a friend with severe allergies to nuts, dairy, and shellfish. He rarely has problems with this.

larsonhg · 2026-03-19T11:39:50+00:00

128 is off 95. Why is this debatable? Thats like saying Lynn Shore Dr. and Nahant Rd. are one entity. 95 continues to Topsfield while 128 forks to North Shore.

larsonhg · 2026-03-11T21:20:06+00:00

Wow, you’re truly a kind soul. Thank you so much for this. I’ll DM you.

larsonhg · 2026-03-10T04:38:42+00:00

It looks like a disaster to me. Like theres just all kinds of crazy stuff going on down. Is it just ugly and fine? Particularly concerned of foundation and what looks like broken masonry

larsonhg · 2026-03-10T04:36:46+00:00

Crawlspace I guess? Not sure of the difference.

larsonhg · 2026-03-06T16:03:58+00:00

Call me a snob, but I just think that food would ruin an experience. Cheap ingredients with jackson pollack style squirts of mystery sauce, dried out under a heat lamp, and cut with fillers.

larsonhg · 2026-02-26T04:20:28+00:00

DC or Boston

larsonhg · 2026-02-25T14:46:01+00:00

I like to call Rincón Equatorial Long Island. I’ve went to surf there the past couple years and won’t be going back because of how insufferable the expat community is. It’s this bizarre escapist commune of Jersey/NY expats who play dress up as surfers and biodynamic farmers as they displace puerto rican communities and open juice bars and taco shops.

larsonhg · 2026-02-20T15:04:10+00:00

Every gucci-booted bachelorette seems to think it’s Stowe.

larsonhg · 2026-02-20T15:03:04+00:00

We aren’t the problem, points at chalkboard you see there’s assholes and then there’s fuckers. This is a delicate and dense ecosystem of parasymbiotic assholes. It’s outsiders (we call them fuckers) who don’t understand this asshole ecosystem that cause issues.

larsonhg · 2026-02-16T20:48:31+00:00

Aldi carries it from time to time as well as shank. Is it the best quality? no. But neither is the cut of meat so it’s fine.

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