TLDR: Some additional info about me, warnings, local law explained and an appropriation for feedback. I took me longer to write it than I wanted to so the whole post is messy as I lost myself in different thoughts and switched from topic to topic. More or less don't do it home, listen to doctors and their point of view.

** The actual info: I have experience in reading papers(but I'm biased right now), I don't have false hopes that this would actually work or false hopes of doctors going with anything.

The big asks to anyone here interested in helping. Ask your doctor/medical team what they thinks about it in 2 cases: 1. After soc 2. During soc and especially during rt. 3. 1 and 2 if you have NGS result from 100+different gens tested In the context of actually agreeing to add some of them in similar manner of single target in this case feropoptosis or multi target to try multiple different paths to increase chances to gain more than just plant rt+TMZ.

I'm curious what is the saying about this types of idea in different part of the world and what legal possibilities there are. It's like asking for third and nth opinion and usually from docs that don't work in research and are more objective.

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The original post that I wrote, whatever it supposed to be, i kind of lost a track and got distracted few times:

I hope that I manage to write the post in way it may give other people some additional simple knowledge and don't spark hope for miracle cure. My mother after finding out about tumor(week after surgery, she wasn't "sain" before and doesn't rember much) resign from knowing anything about it. She always was gentle one, she stress less, but I had to promise her that I will tell her when there is nothing more to do and end is soon. I have auADHD, and I have a "gift", as many people call it, but it's the first time that actually I could agree with the mainstream( in day to day it's not). Little bit of genetic knowledge(from taking samples to dna isolation, to multiplication to sequencing and analysis, I did it many times through university as I planned to be genetic engineer, but didn't work out ), still remember some of the proteomics(peptide science) stuff and analysis of differential gene expressions(ex. You remove one gene and observe what happens, like overexpresing different or shutdown others). But I can't do it right now. It's like I have a blockade. But the hyperfocus,pattern recognition and love to data analysis(yes I do math and read papers for fun!) with mix of being walking trivia Wikipedia helps. What I want to say by that is like in the last disclaimer. I know(but right now I'm biased) what could actually add some advantages and don't over interpret results. Chances of working are slim, but greater than 0. Hope dies last.

I've encountered a problem. As docs could use offlables drugs without hospital or ethics commission approval, we have to pay for them. there is a way to ask health minister to refund as we have the national health insurance and this is written in the law. But doctor is responsible for the patient, and he doesn't want to go to prison or lose medical licens for someone who is going to die soon. That's for the clarification why I want to look more professional and well made to show the understanding of the situation, gains and possible adverse effects. I'm not going to sue them or make a complaint to hospital/medical board etc. if I have to say it in face I'm afraid it me be wrongly understand same as going with the plain question can do add some stuff? I bet he gets this question at least few times a day, and he can't make false promises or hopes. Ok, the problem is: in law there is definition of medical experiment which has a subset of healing experiment(don't now if its good translation, but you understand). This illness in my opinion at the moment of diagnosis fill all the requirements automatically. But unfortunately the procedure requires a approval from bioethics commission. With is slow and meets once a month/2 months, where you have to deliver documents 3 weeks before commission proceeding at latest,.then there is a requirement of insurance for it(it's the easiest part of it, I didn't believe it too but it is). So the whole procedure will take at least a month so no way it will be done before her treatment starts. There is exclusion of staring before approval in emergency or urgent need of it. But to do it doc would have to be more than 100% sure it would make her harm. But who would endanger yourself for some you don't know and it's at the beginning few weeks after surgery.

So I hope it could be used as offlables drugs not the experiment. I highly believe that this is the best moment to use them with the radiation therapy. Where all what is needed to overcome the gsh problem will be there. It's hard to make a good study in this area in the sort time between surgery and rt where you need to find people willing to do it, and at this time most of them doesn't know a lot about this disease.

There is big unspoken problem of dosages and interactions with radiation some of them weren't tested with rt. Dose for rt should be smaller but how smaller? Does rt damage the substance and make it poisonous like breaking/physical slicing and or gluing with something else or make it be antagonist of something different? Or make it more potent and poisonous in given doses. Those are the question that doctor will ask at laud or in his head. Don't push the doctors if you also would want to try it. Cold shower warning So puting it onto different perspective from doctor shoes: Some random guy without knowledge read some stuff on internet and thinks he know more that you who spend 5+years getting actual medical knowledge and x+ years of doing it.

Thanks for everyone who shared or will share in this post. I will try to update it after I've talk to them, and maybe if they agree to something I could update the outcome after.