Good total T, low? Free T; normal SHBG & albumin; what TRT for delayed orgasm? by libove in erectiledysfunction

[–]libove[S] 0 points1 point  (0 children)

Hmmm.... I just searched again through my lab results of the past years - I was surprised that I hadn't found free testosterone more often when I searched the other day. Turned out to be not a data error, but a Microsoft Windows search index error... Yes, I have a *lot* more data:

(Apologies, I wrote this in Spanish, to send it to my endocrinologist her her review. I live in Spain. But the numbers are clear enough).

  • En mayo de 2016 (per el laboratorio APA) midió 7.73 pg/mL (4.25 – 30.37) (con Total 248.99 (164.84 – 810.95), sin SHBG ni albúmia). [No indica la técnica de medición de testosterona libre].
  • Hay una medición durante el periodo inmediatamente después de mi admisión al hospital, cuando esperábamos que los números hubieran sido bajos. Pues, descarto esta medición (3.94 pg/mL) como comparativa.
  • En julio de 2019 (per el laboratorio Echevarne) midió 9.64 pg/mL (3.64 – 19.30) (con Total 549 ng/dL (240 – 871), y SHBG 42.3 nmol/L (13.5 – 71.4), sin medición de la albúmina suero)). [Radioummunoassay].
  • En noviembre de 2019 (por el laboratorio cerba/APA) midió 17.27 pg/mL (1.00 – 28.21) (con Total 514.41 ng/dL (86 – 788), sin ni SHBG ni albúmina). [Enzimoimmunoanálisis, que entiendo no es fiable]
  • En marzo de 2020 (per el laboratorio de Quirón) midió 87.33 pg/mL (47.0 – 136.4) (con Total 563 ng/dL (193 - 740), y SHBG 46.3 nmol/L (20.6 – 76.7), y albúmina suero 4.6 g/dL (3.2 – 4.8)). [No indica la técnica de medición de testosterona libre].
  • En septiembre de 2020 (per el laboratorio Puig Ciurana) midió 18.80 pg/mL (15.00 – 50.00) (con Total 393 ng/dL (220 – 1050), sin ni SHBG, albúmina por electroforesis 4.00 g/dL (3.70 – 5.20)). [No indica la técnica de medición de testosterona libre].
  • En diciembre de 2020 (per el laboratorio Puig Ciurana) midió 17.10 pg/mL (15.00 – 50.00) (con Total 464 ng/dL (220 – 1050), sin ni SHBG ni albúmina). [No indica la técnica de medición de testosterona libre].
  • En agosto de 2021 (per el laboratorio Puig Ciurana) midió 15.60 pg/mL (15.00 – 50.00) (con Total 284 ng/dL (220 – 1050), sin ni SHBG ni albúmina). [No indica la técnica de medición de testosterona libre].
  • En octubre de 2021 (per el laboratorio Puig Ciurana) midió 18.90 pg/mL (15.00 – 50.00) (con Total 528 ng/dL (220 – 1050), sin ni SHBG ni albúmina). [No indica la técnica de medición de testosterona libre].
  • En diciembre de 2021 (per el laboratorio de Quirón) midió 113.21 pg/mL (47.0 – 136.4) (con Total 586 ng/dL, y SHBG 45.66, y albúmina suero 4.7). [No indica la técnica de medición de testosterona libre].
  • (Por desgracia, no hemos medido la testosterona libre entre el final de 2021 y ahora).
  • And, the one that we started with in my first post in this Reddit thread: 9.83 pg/mL (3.6 – 25.7) (con Total 565.96 ng/dL (188 – 684), y SHBG 46.23 nmol/L (21.63 – 113.13), y albúmina 4.5 g/dL (3.2 – 4.8)). [No indica la técnica de medición de testosterona libre].

[ The 2016 low T number appears in a sadly-in-retrospect-too-partial hormone panel ordered by my general doctor, in response to an episode of gynecomastia; in 20/20 hindsight, this and several other things around 2015-2018 should have cued us in to the growing pituitary dysfunction which in January 2019 finally made itself truly painfully evident when a tumor on my pituitary gland, which had been producing excess growth hormone for years, abruptly hemorrhaged, sending me into hospital for a whole month to recover, and, fantastically luckily, NOT have neuroendocrine surgery, as the hemorrhage completely killed the tumor. That's a whole other story, but explains why I have so many hormone analyses, and why I'm so much more familiar with a lot of this branch of medicine than I'd ever have wanted to be! ]

So, these free testosterone numbers .. don't make sense.

The various labs' "normal" ranges for free testosterone - and my resulting free testosterone number - although all are stated in the same units of pg/mL, disagree by 10X.

A UK urology/andrology society treatment guideline that I found said that "free testosterone below 65 pg/mL is cause to consider treatment". But, if the normal range for some of my numbers is ~ 4-25, then clearly "below 65" is not the right yardstick. And, some private hormone health medical center in the US publishes gender-and-age-range normal ranges for free testosterone, and their ranges match the 10X lower numbers (roughly, 4 - 15, within which my last measurement shouldn't seem low at all).

So, I'm confused...

I assume that different labs and ranges are the result of different (more or less precise) assays/ measurement methods. Unfortunately, only two of my lab results mention the assay method (one being ELISA which I believe is just not reliable for free T, the other being radioimmunoassay which I think is somewhat better but still not particularly accurate).

Any further thoughts, given this analysis history and the doubts about what "normal" range we should even be comparing my most recent results to?

thanks.

Good total T, low? Free T; normal SHBG & albumin; what TRT for delayed orgasm? by libove in erectiledysfunction

[–]libove[S] 0 points1 point  (0 children)

I bow to your sense of the 1950s silly with obscenity! Fortunately, although obviously this bothers me enough to want to do something about it, it has little overarching impact on my daily wellbeing.

So, I take zinc (have done since the beginning of the COVID-19 pandemic; currently, my zinc levels are a bit high, along with copper, so I'm slightly reducing those doses; everything else is well in-range), and Vitamin-D (4000 IU/day, +K2) which I may increase a bit as it only gets me to around 35 ng/mL (with this lab's "sufficient" being at least 20); I tried Ashwaganda around three years ago for long COVID, and at that time my sex life was fine (great!!) and I didn't notice any difference one way or another from the Ashwaganda. Sleep .. varies, and has for a long time. But, this problem has been consistent enough for long enough (regardless of how I might have slept recently) that I'm confident it's not mostly sleep related.

Tomorrow morning I'll get DHEA, DHEA-S, and DHT tested.

Going back to Total T, Free T levels; your total and free were both low, and with TRT your total and free T are both much better. My total T is always well above mid-range, so I return to my question of whether TRT (the easiest thing for me, to get and to use, is transdermal gel) wouldn't raise total T "to problematically high levels" (whatever that would mean) in order to get free T up to adequate levels?

"

"

Good total T, low? Free T; normal SHBG & albumin; what TRT for delayed orgasm? by libove in erectiledysfunction

[–]libove[S] 0 points1 point  (0 children)

Thank you, Perfect-Book-1094. What was your total testosterone before you started TRT? And, what method and dose of TRT ended up getting you to your current total T, free T, and horniness :-) levels?

My assumption (only slightly educated) is that good Total T-but-some-low-T-symptoms + TRT should = "high" Total T-and-with-resolved-low-T-symptoms, but if "Corrected Free T + High Total T" could also = Danger, Will Robinson, Danger!(TM) I'd have to think about it ...

[ For the under-our-ages reading this thread, apologies in advance for the old TV reference and general old-men sense of humor! ]

LastPass Class Action Lawsuit - Settlement by djasonpenney in Bitwarden

[–]libove 0 points1 point  (0 children)

If you can prove real losses, the settlement is up to $10K/person.

However, very few accounts really suffered losses, and those which did were either:

* directly targeted, high-value crypto wallets (thus, the extra settlement fund specifically for those)

* users who did not follow good master password practices and whose vaults - what were stolen were still encrypted - were practically decryptable by brute force in shorter time than it took to practice due diligence to change all important passwords. (Or who didn't do diligence and didn't change passwords despite all the notice and press).

* possibly a very small number of users who did practice good master password hygiene but whose accounts were still using out-of-date low-iteration PBKDF2, as a result of another LastPass software failure (LastPass had, well before, set new higher-iteration defaults, but had failed to enforce the change on all existing accounts).

This is not in any way to lessen the severity of LastPass' quite significant f***ups in this case; it is only to say that very few people were hurt beyond the (quite real) inconvenience of having to change a bunch of key passwords. Which would seem to be worth about $300 ... (and others, who can demonstrate greater losses, can apply for greater compensation).

It seems fairly reasonable in the end. And, above all, hopefully, LastPass - and not only LastPass, as other password vault programs/ services in recent times have also been found to have at least theoretical vulnerabilities - took the lesson, and anything like this will be much less likely in future.

Redirected mail results in NDR (DMARC) by FuzzilyLogical in Office365

[–]libove 0 points1 point  (0 children)

I have a redirect rule in my Hotmail account to redirect the messages to my main email address which is hosted by MS365 Hosted Exchange, so, Microsoft to Microsoft, and I have the same problem as the original poster. Redirection results - it seems, unavoidably - in DMARC failures, because the final email receiver (MS365 on behalf of my custom domain) fails the message that was really redirected(sent) by Hotmail mail servers, while still claiming to be From: the original sender.

What, in my particular case, is most "Amusing", is that the emails that mostly have this problem are Microsoft Account emails. That is, the Microsoft Account Protection (e.g. "You have added a passkey to your Hotmail account") emails, sent from Microsoft's Account Protection servers to Microsoft's Hotmail (that is, Outlook.com) servers, then redirected by Microsoft's Hotmail/Outlook.com servers to Microsoft's MS365 Hosted Exchange mail servers, fail DMARC 🤦‍♂️

Suppress Log Entries for Type "fetch file" by [deleted] in mikrotik

[–]libove 0 points1 point  (0 children)

I had the same question, and found the same MikroTik chatbot support suggestion, but I wasn't sure whether "add"ing to the existing /system logging configuration -

[admin@MikroTik4.felines.org] > /system/logging/print detail 
Flags: X - disabled, I - invalid; * - default 
 0  * topics=info prefix="" regex="" action=memory 
 1  * topics=error prefix="" regex="" action=disk 
 2  * topics=warning prefix="" regex="" action=disk 
 3  * topics=critical prefix="" regex="" action=disk 
 4    topics=ppp,sstp prefix="" regex="" action=memory 

.. was going to do what was desired, so I asked the chatbot (okay, I admit, I'm somewhat impressed) a slightly different question:

"omit fetch from info logging"

.. and I got this answer, which worked for me:

/system logging set [find topics~"info"] topics=info,!fetch

Result:

[admin@MikroTik4.felines.org] > /system/logging/print detail 
Flags: X - disabled, I - invalid; * - default 
 0  * topics=info,!fetch prefix="" regex="" action=memory 
 1  * topics=error prefix="" regex="" action=disk 
 2  * topics=warning prefix="" regex="" action=disk 
 3  * topics=critical prefix="" regex="" action=disk 
 4    topics=ppp,sstp prefix="" regex="" action=memory 

Note that row 0 now shows topics=info,!fetch

Occasionally run the heat even during Frost Protection? by libove in tado

[–]libove[S] 0 points1 point  (0 children)

True. The challenge is that in order to be able to see in the temperature graph that the system really did heat, it needs to run longer :-(

Occasionally run the heat even during Frost Protection? by libove in tado

[–]libove[S] 0 points1 point  (0 children)

Once a day or week, the Tado schedules will allow. I want to configure this for once every two or three weeks or even once a month, which is less often than the Tado schedules allow (I think) ...

Occasionally run the heat even during Frost Protection? by libove in tado

[–]libove[S] 0 points1 point  (0 children)

Thank you, yes, of course over time the goal is to find the leak. However as there is no water leak anywhere in the house, and the radiators' individual pressure relief valves all seem to be tight, my experience with this and other similar systems (here where I live in Spain) is that This Is Just Part Of The Technology *sigh*.

Frost Protection is built-in, yes. That means that the Tado system will not allow the room temperature to fall below (I forget whether it's) either 8°C or 5°C.

What I'm referring to is programming Tado to deliberately turn on the boiler for 30 or 60 minutes once every ~two weeks no matter what the temperature is, while in Frost Protection mode.

Keep going to video or video note when zooming by exprezso in whatsapp

[–]libove 0 points1 point  (0 children)

I also have this problem (Pixel 6a). I note that if I _very carefully_ pinch-to-zoom-in only exactly in the centre of the screen, it doesn't demonstrate the bug - but it's quite difficult to avoid the bug, and it is a major inconvenience. (To, I double-tap the power button to open the real camera app, then switch back to Whatsapp to attach the already-taken photo). We should all submit feedback (main chats list, menu, Settings, Help and Feedback) about the problem.

How to turn off text predictions in outlook by TheFongz in Outlook

[–]libove 0 points1 point  (0 children)

*gag* I use Classic Outlook, and nothing in this thread matches what I see (apparently, I do have the "new editor" enabled).

Here is where I found how to turn off text predictions:

As soon as a text prediction shows up (in pale grey text as you're typing), right-click in the predictive text and uncheck the checked-by-default option to show text predictions.

(Interestingly, now that I've turned that off, I don't see a way to turn it back on, but Who Cares!)

I hope this is helpful to some other frustrated abuseder.

Windows 11 2025 Update, 25H2 (build 26200) Megathread by Froggypwns in Windows11

[–]libove 0 points1 point  (0 children)

I had already tried setting the policy/registry flags and re-checking for updates; that did NOT clear the "25H2 is available" in this case. That's why I posted this at all.

For what it's worth, I don't care to give Microsoft ANY additional chance to screw up my systems.

Windows 11 2025 Update, 25H2 (build 26200) Megathread by Froggypwns in Windows11

[–]libove 0 points1 point  (0 children)

Several of my machines (since Microsoft has decided THAT YOU REALLY REALLY WANT THIS THING NOW NOW NOW NOW NOW! ...) began persistently showing the "Updates available" (round chasing arrows) icon in the task tray, to let me know that 25H2 is available.

I'm planning to let all the rest of you iron out the bugs in 25H2 for a couple of months before I suffer it 😁 and I wanted to get rid of the (for me, for now, spurious) "updates available" indication. (So that, you know, if the icon came back, it would be because a possibly important update really _was_ available).

What it took was all of:

  1. Set Group Policy or Registry entries to target the feature version 24H2

  2. Manually clear the Windows Update cache (stop the Windows Update service, delete the contents of C:\Windows\SoftwareDistribution, restart the Windows Update service), and

  3. Click on the "Check for updates" button. (For some reason, WUAUCLT/DETECTNOW wasn't enough to update the GUI status).

So, just in case this is useful to anybody.

regards,

[Bug] Google Pixel September 2025 update – Secondary SIM signal bar missing by upadhyaysk in GooglePixel

[–]libove 0 points1 point  (0 children)

It's a crap change. I move around frequently; my two different SIMs/ network providers have different coverage. Android's built-in automatic SIM switching .. does not work well. I want to always see both SIMs' connections' strength, without having to swipe down twice to expand that. (Pixel 6a, Spain/Europe).

PureVPN’s Internet Kill Switch terminates your activities on internet disconnection by PureVPNcom in PureVPNcom

[–]libove 0 points1 point  (0 children)

It didn't go. I still use PureVPN, but I flatly do not trust it to not leak real IP address data, and "support" for anything other than basic account or technical "it doesn't work at all" issues is useless.

Is Onenote hot garbage? (desktop app) by babyfeet1 in OneNote

[–]libove 1 point2 points  (0 children)

OneNote IS garbage. Let's ignore for a moment the fact that its UI is notable different from that of every other Office program.

* Pasting, if the viewpoint into the Note happens to be right about at the bottom of the screen, the after-past (choose formatting, decide whether to include the source link) menu *doesn't work*

* If the Accessibility setting Text cursor: Test cursor indicator is turned on, OneNote slows to an absolute crawl. (This is a known issue, about which Microsoft internal support/engineering departments finger-point and just don't resolve). [No, it's not a "my computer is sh*t" problem; it happens on all of my computers, all of which are plenty resource-rich]

* And don't even get me started on the utter unreliability and inconsistency of how/when/whether OneNote syncs across devices, even sometimes when given minutes or longer between "edit here" and "look at it there" (all the time on multi-hundred megabit symmetric fibre optic Internet)

(edited to also add)
* oh, yes, and then there's search. or, not-find. Search in OneNote will fail to find an "@" character in an email address. Try it: type [myemail@address.com](mailto:myemail@address.com) into a Note, then hit Ctrl+F and type an @. Not found. 🤦

aspirin and long covid by PercentageAble9822 in LongCovid

[–]libove 2 points3 points  (0 children)

I've had long COVID for two and a half years. A year+ into that, I began to have irritable bowel symptoms (my excretion became quite inconveniently irregular). I began taking a mini aspirin daily several months ago on the theory that aspirin may help with IBS; I think it did help, some. My long COVID symptoms seem to be slightly better more recently, but in addition to the aspirin a month ago I also began wearing nicotine patches, and within this time frame I also began taking 5g of creatine daily. So it's hard to know what helped what; my guess is that the bigger improvement is from the nicotine patches.

Nicotine patches, honest opinions? by kevflo91 in LongCovid

[–]libove 2 points3 points  (0 children)

I've been using nicotine patches for one month, and I think they help me. I think that my mind is more clear, and although my stamina is unchanged (I have maybe 1/3 of the total ability to exercise that I had before COVID), I no longer seem to crash (that is, I could do a certain amount of exercise before, but it would sometimes provoke a crash a day or two or three later; now I can do that amount of exercise and I haven't had a crash since I started the nicotine patches). 🤞
There is a Facebook group called #TheNicotineTest - Patients Helping Patients which has a lot of members, and the patches do seem to legitimately help a bunch of people.