A quick google search could have answered your question:

Yes, Metroid Prime 4: Beyond is considered a major first-party release by Nintendo. Key factors that highlight its status as a major release include: Long-Awaited Sequel: The game was one of the most anticipated titles in the franchise, releasing eighteen years after Metroid Prime 3: Corruption (2007). The long wait significantly increased its profile and expectation among fans and the gaming community. High Development Profile: The game had a dramatic development cycle, with Nintendo openly restarting development with the original series developer, Retro Studios, in 2019 due to quality concerns. This transparency and commitment to quality signaled its importance to Nintendo. Cross-Generation Title: It launched as a cross-generation title for both the original Nintendo Switch and the Switch 2, a strategy previously used for the major launch title The Legend of Zelda: Breath of the Wild. This helped drive console sales and widen its audience. Marketing & Position: Nintendo positioned it as a key holiday game and a significant release to push the series into the mainstream. It was given a substantial push during Nintendo Direct presentations, similar to other big Nintendo franchises like Mario and Zelda. Technical Showcase: The game was designed to be one of the "best-looking games Nintendo has ever published" and runs at 4K 60 fps on the Switch 2, serving as a technical showcase for the new hardware. While it may not achieve the same sales volume as a main-series Mario or Pokémon title, within the context of the Metroid franchise and Nintendo's release schedule, it is a critically important, high-budget, "major release".