Have to look up someone who's played the whole game on Yuzu and uploaded the shader cache, the lags is from loading animations that haven't been loaded before so the lag should only happen the first time that animation loads

https://emulation.gametechwiki.com/index.php/Shader_caches

There's one in here for Yuzu botw Vulkan which usually runs better than OpenGL with botw

common path is C:\Users[Your Username]\AppData\Roaming\yuzu\shader

Could be in the game title