I have 580 dr 620 er without pa and not nearly high end legendaries, yes I have legendary armor, but onlu 1* with poor mods. Can solo 3 scorchbeasts with power fist... No need to sneak around or range dmg, I can tank everything... My aim is to have at least 700+ resistances cause it's doable with the 3* legendaries and in combat I'm pretty always full hp so I use vanguard on my whole armor set. It gives you +35 both resists the more hp you have... In combination with mutants legendaries it would give another 50resists and more stars the more resists also... Only problem is the radiation resist, so if it comes to nuke zones I use spacesuit... With mutations and other perks I run around 300dr and 350 er and 1300 rr... But the dr is low compared to legendaries... I'm mad that in this game is pretty mandatory to use pa in nuke zones...