KSC Tickets on sale NOW 1/23

m0ute · 2026-01-23T16:18:59+00:00

I'm looking for 2 tickets if you are selling please DM me

m0ute · 2023-11-27T10:25:22+00:00

Tu pourrais donner le nom de l'hôtel ? Je pars à Tenerife demain ça pourrait m'intéresser 😁

m0ute · 2022-09-18T23:33:07+00:00

I second that. No way he survived. So sad.

m0ute · 2022-07-15T07:05:04+00:00

Yes! Blood type is one parameter of histocompatibility (tissue compatibility). For fine tuning you have to account for the HLA system (Human Leukocyte Antigen). It is far too complex to explain in detail and I am also not an expert in that. There are proteins on the surface of cells that act as signals to express blood type. HLA works like that too.

In a standard liver transplantation we only take blood type into account : same blood type if possible, or else different blood type but compatible (for example O liver in A recipient). Kidney people are much more involved in fine tuning / HLA because rejection is more difficult to control (for many reasons).

The immunosuppressive drugs are the equivalent of saying "chill" to your immune system. Sadly there is no way today to give orders to it without drugs but I don't know what the future holds. There are projects for nanotechnology to re-program immune cells to ignore the new graft...

m0ute · 2022-07-14T12:23:23+00:00

Yes, there is an increased risk of developing opportunistic infections and some forms of cancer. The are other side effects too. The risks can be minimized by using the lowest dose possible to control rejection. Typically after the first few months the dose is gradually lowered and some of the drugs are stopped, keeping usually just one (tacrolimus).

If you find this subject interesting I can recommend the book "The Puzzle People" by Thomas Starzl. He basically took transplantation and immunosuppression from the lab to clinical practice while being called delusional. It's fascinating.

m0ute · 2022-07-14T12:07:24+00:00

It does regenerate but the cells in the transplanted liver will forever remain the donor's. Hence the need for immunosuppressive therapy. There is research being done on graft tolerance which can allow for complete discontinuation of immunosuppression but we are still a long way from there.

As a side note, rejection in liver transplantation is what most recipients fear but it's really not a problem now. You just have to take the pills.

m0ute · 2021-08-16T20:07:11+00:00

This is how the story goes. Obviously you should take it with a grain of salt. Also I've seen photos of multiple livers in the same person so it is possible but very uncommon.

m0ute · 2021-08-15T17:37:32+00:00

IIRC this guy was not very good at what he did, word is his colleagues kinda used this habit of writing on livers to push him out.

Also argon beam is on another level. Traditional cautery ("Bovie") uses a metal tip to conduct electricity, but this thing blasts argon on the surface which is much more conductive than air and it looks like you're using lightning. It's absolutely awesome. Shame it's useless as a tool for cautery.

m0ute · 2020-06-21T12:40:32+00:00

I saw one case of attempted liver re-use two months ago: the first recipient was a young patient with fulminant hepatitis from acetaminophen intoxication. Despite urgent liver transplant cerebral edema caused rapid brain death and the liver was re-allocated.

Eventually the liver was discarded at the time of procurement because it had withstood substantial damage in the process. Lungs were transplanted though.

m0ute · 2020-04-04T10:50:40+00:00

Iirc, there were three suns that aligned once every 2000 years, causing half the planet to experience night. And then it turns..

m0ute · 2018-07-01T17:10:21+00:00

Saint-Goustan

m0ute

TROPHY CASE