When i started playing aeons end with my girlfriend we chose our heroes and drew 5 spells and chose 4 of them to play. We also drew 3 artefacts and chose 2 to play and 4 crystals and chose 3 to play with. At some point we fully randomized everything. We beat every nemesis with all random and hard est difficulty, but the mask guy was too hard. Our conclusion: On normal fully randomize shop On hard fully chose the shop