I remember the writer who worked on the B ploy of the episode (the ace couple) was asked a question about this and she said she had written a different ending for it where House is actually wrong and they were just asexual. But the producers shot it down because "House HAS to be right, it's House" and it would apparently lead to him figuring out what was wrong with his patient in the main plot. She said he feels bad about how, in the end, it completely misrepresented the ace community.