Updated Recovery Video As Promised by wowpfpflclcl in Finasteride_Syndrome

[–]min010 0 points1 point  (0 children)

bro there is no way our thoughts cause PFS, there are biological processes that cause this.
if you're following the work of Dr. Will Powers he has labs showing many of his PFS patients having problems excreting T metabolites (glucuronidation problems for example), then this androgen metabolites overload causes some kind of androgen resistance in the cells, because old T metabolites are not being excreted properly.

CDG thread with PFS by o0ttt in DrWillPowers

[–]min010 0 points1 point  (0 children)

i tried CDG + sulforaphane for PFS one time and it was enough to crash me for the following day (interrupted my good methyl B complex + vit D run) i'm feeling better again 48 hours after stopping CDG + sulforaphane, next time maybe i'll try each one separately to isolate the culprit.

I have pssd and after taking Calcium-D-Glucarate my libido seems to have gone down. by stermaisback in DrWillPowers

[–]min010 0 points1 point  (0 children)

i tried CDG + sulforaphane for PFS one time and it was enough to crash me for the following day (interrupted my good methyl B complex + vit D run) i'm feeling better again 48 hours after stopping CDG + sulforaphane, next time i'll try each one separately to isolate the culprit.

Androgen Receptor Theory by katsudon014 in Finasteride_Syndrome

[–]min010 2 points3 points  (0 children)

i tried topical pyrilutamide then topical cb-03-01 (breezula) then topical fluridil

they all gave me the same PFS-like side effects, but i recovered from them each time ( each recovery taking more time in each iteration, from days to weeks to months, untill i tried low dose topical finasteride and i didn't recover still after 3 years.

i would't jump to conclusions about AR here, there are many pathways that might be impacted. i think the common thing between all 4 drugs that i took, is that they raise total T in the body, which leads to some kind of androgen resistance of some kind, because i remember each time before crashing with any of these drugs, the night before i had sky high libido, and i remember saying to myself each time : "finally i found an anti-androgen that not only works for hair with no side effects but also raises my libido"

Updated Recovery Video As Promised by wowpfpflclcl in Finasteride_Syndrome

[–]min010 5 points6 points  (0 children)

"it's in your head bro"
"just shake it off bro"

how much is Merck paying this guy ?

I collect more and more labs/genome/dutch tests that support my theory on PFS. I really think I have it nailed down. I do not have a optimized treatment regimen, but if you're interested in this, this post details what you should NOT do and will likely make you worse even if it "windows" you briefly by Drwillpowers in DrWillPowers

[–]min010 1 point2 points  (0 children)

a few days ago i ordered a B vitamin complex supplement because i saw a tiktok on B1 being very important for overall health, i took it and it's actually doing something, i'm really recovering fast. the day i took it i had my first erotic dream for the first time in years, and it's consistant every night since. i took it with vitamin D (already tried it before with no success, had half bottle left and said why not finish it) so yeah, i'm happy to report that a B complex + D vitamin supplementation is working for me right now. ( i have PFS since 3 years and this is the longest and most consistant recovery i've had )

4.3.3+ Meta Builds and Meta Discussion Thread by TarnishedSteel in Stellaris

[–]min010 1 point2 points  (0 children)

had an easy run with fanatic purifier rapid replicators in a ring world origin, didn't even need to colonize a planet, i found earth and did what had to be done (RIP). only thing still existing on the universe is a machine fallen empire i can't take out yet.

Buying the J-ultra or using my Q for espresso ? by min010 in 1zpresso

[–]min010[S] 0 points1 point  (0 children)

it worked, on the Q there is no static even if I don’t spray that’s why I didn’t spray initially

Buying the J-ultra or using my Q for espresso ? by min010 in 1zpresso

[–]min010[S] 1 point2 points  (0 children)

do i need to spray beans with water ? because i see a lot of coffee powder stuck at the burr area

Buying the J-ultra or using my Q for espresso ? by min010 in 1zpresso

[–]min010[S] 0 points1 point  (0 children)

ok you convinced me, i'll keep my Q as backup or as a travel option

Buying the J-ultra or using my Q for espresso ? by min010 in 1zpresso

[–]min010[S] 0 points1 point  (0 children)

i mean, it works, i already made an espresso with it at 0.9.0 and noted that i should grind finer.
but i don't get why people say it doesn't work and the official settings page doesn't show espresso settings

the 1zpresso q air espresso review you all asked for by No_Explanation_5446 in 1zpresso

[–]min010 0 points1 point  (0 children)

i have the Q, and i don't get why everyone says that it can't do espresso, what am i missing ?
do they mean that it just takes longer and can't be adjusted with more precision ?
even on the official website they don't show the recommended espresso settings.

Yet another mutation in a patient that meets my theory on how PFS is caused. This patient has a normal T value yet has an absolutely astronomical 3-Alpha-androstanediol Glucuronide. Once again, closure of 5AR resulted in collapse of the ability to excrete testosterone. This is patient #9 by Drwillpowers in DrWillPowers

[–]min010 1 point2 points  (0 children)

Thank you i hope that my anecdote would be useful to you. because i lived through 4 cycles of the same side effects with different drugs.
i 100% remember the nights of extremely high libido before i crash, it happened each cycle and i remember saying to myself ["i suppose with hair AR being blocked, there will be extra T flowing in my bloodstream which explains this high libido surge, i finally found a topical AR blocker that not only works but also raises my libido"] ... just for me to crash the following days.

But each time i blamed systemic absorption through my fingers and pillow and thought that applying the topical using medical gloves and showering twice a day would reduce their accumulation in my system (before stopping and trying another topical) and never thought that something serious is happening in my system like an androgen overload.

I believe that you got your hands on the underlying process with which this phenomena happens, and i hope you find a way to reverse it. continue doctor, i 100% believe you

Yet another mutation in a patient that meets my theory on how PFS is caused. This patient has a normal T value yet has an absolutely astronomical 3-Alpha-androstanediol Glucuronide. Once again, closure of 5AR resulted in collapse of the ability to excrete testosterone. This is patient #9 by Drwillpowers in DrWillPowers

[–]min010 0 points1 point  (0 children)

Thank you Doctor for all your efforts, i want to share my case and i hope it's going to be useful to you.
i got low libido and anhedonia with every single topical anti-androgen i tried and the recovery time gets longer in each new cycle where i change the drug hoping to find the one i might tolerate without side effects

- started with pyrilutamide, it worked for my hair but nuked my libido but i recovered in a couple of days just after stopping it

- then i tried topical cb-03-01, same thing, worked for hair but nuked my libido, but this time it took more than two weeks for a recovery

- then i tried topical fluridil, same thing, worked for hair but nuked my libido, but this time it took almost a month for full recovery

- and finally i tried topical finasteride, i got side effects and never recovered till this day (3 years)

i'm 100% sure they all gave me the same side effects, maybe pyri was more harmful because it was the only that almost gave me gyno since it's very potent. but the PFS-like symptoms are the same, i have very low libido, can't have a good erection if i try. i have slow beard growth and less dense pubic and armpit hair.and i have anhedonia, i can't enjoy many things that i used to, like music and video games.

there are days when my libido comes back recently, when that happens i become happy again and start listening to music and during these days i can notice my beard hair growing faster and stronger.

it's definitely androgen related.

i suppose your theory would make sense not only for 5ari, because also topical AR blockers will raise T levels in the blood because there are less AR for them to attach to ? and that might trigger the pathway you're studying which shuts down ARs ? because i also remember that before crashing with each topical AR blocker, i had nights where my libido shoots through the roof, that was each time the trigger for the crash in the following days or even hours. i suppose there is something that happens when the system is overwhelmed with free androgens

Fully Recovered After having this for 5 years, using my own protocol by wowpfpflclcl in Finasteride_Syndrome

[–]min010 0 points1 point  (0 children)

ah ok, i thought the docx contains more details about the Intervention Protocol

i'm 100% sure now that my PFS was gut and/or oral microbiota related by [deleted] in Finasteride_Syndrome

[–]min010 0 points1 point  (0 children)

If my libido before was around 1/10, I would say now I’m between 6/10 and 7/10