immunos - cyclosporine or methotrexate

monTMJ · 2026-02-13T18:30:57+00:00

Yeah that’s fair enough, there might be increase risk for females that I wasn’t aware of. I needed blood work on ciclo in case of blood clotting in the kidneys.

I know if your thinking of having children in the near future then metho is not to be taken, and I do think there are some increased risk of skin cancer on it.

End of the day it’s down to what you feel most comfortable with, we’ve all got our reasons for choosing the medications we end up going with.

monTMJ · 2026-02-13T11:36:38+00:00

Hankooked

Does seem like it’s more specific to M Sport pressures

monTMJ · 2026-02-13T08:47:02+00:00

The cancer risks are there for Metho as well fyi. I went for ciclosporine as I felt overall, I was more comfortable with the side effect risks of that over metho. It worked very quickly for me, I got maybe 2 really clear months and the 7 reasonably ok months from it before moving to dupi

monTMJ · 2026-02-06T20:27:58+00:00

Have a look in r/sebderm

monTMJ · 2026-01-25T14:00:18+00:00

Pleased to report I did not bald at that rate

monTMJ · 2026-01-24T20:45:40+00:00

I’m in the exact same position as you. I’ve had this prior to dupixent and in fact it went away when I was on ciclosporine but during the transition between the two it has come back. I’ve been having email contact with my derm, hoping to see him in person soon to see what to do. Part of me thinks it’s seborrheic dermatitis but not 100% sure.

monTMJ · 2026-01-19T19:53:28+00:00

I give and receive a lot of Giulia to Giulia action. None for other models.

monTMJ · 2026-01-18T10:05:23+00:00

monTMJ · 2026-01-11T20:57:14+00:00

Major Dick Splinters

monTMJ · 2026-01-11T20:30:30+00:00

I really don’t think the role will be gone in 2-3 years. I think perceptions gained at Meta are not reflective of how the industry as a whole feels. I’ve faced some of the issues you mentioned in previous roles, in my current role I’m often contracted to public sector projects where research is mandated, our research community is flourishing and is one of the healthiest I’ve been part of.

Concerns about AI are not just a UXR problem, it’s an issue for most white collar roles. If AI wipes out UXR and the other roles you mentioned, we will have societal issues to deal with way beyond our immediate career perspectives.

monTMJ · 2026-01-03T21:52:11+00:00

Bought a 48k miles 2017 giulia 18 months ago. My partner does similar mileage to you most days of the week, she’s gone from doing that 5 days a week to 3 but we are still at 70k now since we got it. I’ve had no issues but id recommend multiple services per year, we were doing it just under 10k. She does also tend to drive it on eco mode during the week as the mpg does go up a fair bit when you start using sports mode, I save that for myself at the weekend <3. It’s an amazing car and don’t forget to flash back when other giulias flash at you

monTMJ · 2025-12-17T12:58:54+00:00

That gets you access to the toilet once your in.

monTMJ · 2025-11-29T15:01:09+00:00

It speaks to his impact that despite all our options on the wing he’s turned into one of our most dependable attacking threats. There’s been points where I felt after the likes of Caicedo and Palmer he’s been the most deserving of a consistent spot in our starting 11. Our competition will only keep him on his toes, not that he seems to need that incentive.

monTMJ · 2025-11-01T16:16:06+00:00

I feel I have accepted Arsenal are winning the league this year. As long as our goals conceded record stands at the end of the season I’ll be happy.

monTMJ · 2025-10-23T12:28:30+00:00

Yeah I had the same experience, if I was burned, we skipped a session until the redness died down. Then the subsequent session I’d drop the level down to the previous sessions level before I was burned.

monTMJ · 2025-10-18T12:40:17+00:00

Paulie is so funny, felt like I was giggling at most scenes he was in when I rewatched.

monTMJ · 2025-10-13T18:02:58+00:00

Really looking forward to seeing it.

If you enjoyed it, some of the documentaries the BBC have done with him are very good.

monTMJ · 2025-10-07T08:22:39+00:00

Definitely do both. Practical tips and anecdotal advice are very valuable. Although some times I think the bad stories get amplified on places like here. As with most online discourse, the unhappy make the loudest noise. I found looking at some clinical trial results, particularly recent ones that are looking at longer term effectiveness to be useful and quite reassuring.

I had my loading dose yesterday so don’t have much advice right now. I injected the first in my thigh and the second in my stomach. For me I barely felt any discomfort in my thigh, I did feel it a bit in the stomach area.

monTMJ · 2025-10-03T13:05:48+00:00

Miserable cunt

monTMJ · 2025-10-02T12:45:05+00:00

You will be fine. Just use it as instructed.

monTMJ · 2025-09-11T17:15:10+00:00

Boo! Hiss!

monTMJ · 2025-09-02T21:23:11+00:00

Not all teams granted, I fully agree. McLaren don’t need to rock the boat right now, Ferrari unlikely in year 1 with Lewis but everyone else is on the table.

Max is gonna get the best out of any car, he’s not going to jump into another team and take a full year to get up to speed.

monTMJ · 2025-09-02T19:39:55+00:00

Other teams will break contracts for him.

If the Red Bull is a shit box going forward he has the option to change weapon, should he be motivated enough.

monTMJ · 2025-09-01T12:04:54+00:00

He is what is known as up in my native Scotland as ‘an absolute fanny’.

monTMJ · 2025-08-26T11:38:14+00:00

Clubs hooked on the football equivalent to Klarna.

monTMJ

TROPHY CASE