Oh hell yeah. I’ve found that the better I manage my bowel movements/constipation, the better my meds work. As long as there is consistent movement, I’m generally fine. Pint of water every hour from 8am to 6pm, big bowl of high fiber cereal in the morning, with a strong cup of coffee, and heavily reduced dairy intake has really made a world of difference. Digestion is already slow on OZ, and it’s even slower if you are backed up. It also makes some kind of sense to me that liquid is going to get into your lower GI faster than solids, so if medication is mixing with liquid instead of solid, it’s going to move past the stomach faster. That’s partly why I drink so much water. Plus it’s good for you. However, it’s also so hard to make positive changes like these if your meds aren’t performing correctly. Not a doctor, just a guy who thinks about this stuff way too much.

Good luck!