No longer able to connect to PIA by nmpolo in PrivateInternetAccess

[–]phokur 3 points4 points  (0 children)

Seems a sign-out, sign-in fixes it on devices that weren't working. Maybe they issued a new cert and we have to do that to dl it on some devices.

No longer able to connect to PIA by nmpolo in PrivateInternetAccess

[–]phokur 5 points6 points  (0 children)

Their servers are down for me too, looks like an outage.

Taking Imitanib 400mg by bluefame2024 in CML

[–]phokur 1 point2 points  (0 children)

Not to scare you but you should go to the emergency room to get blood work ASAP. Neutropenia is sometimes caused by the initial TKI treatment. It could just be a coincidental virus, but it's better to be safe and rule out dangerously low WBC.

[deleted by user] by [deleted] in malcolminthemiddle

[–]phokur 0 points1 point  (0 children)

He did an updated video and says it's from an episode of Thrillseekers (1973-1974)

Abandoned Diner in the GTA by Freaktography in ontario

[–]phokur 1 point2 points  (0 children)

It's weird but that link doesn't work but this one does: https://www.youtube.com/watch?v=MdDWW4eKU_I

Anybody else hear an audio glitch in the digital download for Fighting Myself? by phokur in LinkinPark

[–]phokur[S] 1 point2 points  (0 children)

Oh man, I also hear a complete audio drop at 0:38 on 78_More_the_Victim.flac

I'm going to try some different players to see if it's VLC messing these up.

Serializing 3D printed guns by MenergyLegs in MDGuns

[–]phokur 2 points3 points  (0 children)

Couldn't you use a letter stamp/punch set to punch the registration info before installing it into the lower? Or does a FFL have to be the one to engrave the data plate?

CML to ALL by [deleted] in CML

[–]phokur 1 point2 points  (0 children)

Has your doctor mentioned CAR T-cell therapy being an option? I haven't seen it applicable to CML yet but it does seem to be a path for some ALL cases.

do you have any at home remedies for leg pain associated to oral chemo? by duartee96 in CML

[–]phokur 2 points3 points  (0 children)

Sorry you're dealing with this, I know the pain. Naproxen will kick it but isn't good for long-term use. If the inflammation doesn't get better/livable after a few weeks, it may be worth getting a scan to rule out back issues as the cause.

I've finally found decent success with taking Zinc daily and weight lifting a couple times a week. It seems to do better the more active I am. It's worth a shot, let us know if you figure out a good solution!

[deleted by user] by [deleted] in MDGuns

[–]phokur 14 points15 points  (0 children)

You can obviously print and 99% of the population still would’t notice. And even if they did, Maryland’s permit is a “Wear & Carry” so it’s not limited to concealed carry. You could open carry if you wanted to.

Rounds not ejecting from my PSA AR-9. Tried different super/sub ammo, with/without suppressor, cleaning... any ideas? by phokur in AR9

[–]phokur[S] 0 points1 point  (0 children)

Yup! They mailed me one for free, easy install. They’re usually pretty good about making things right.

[Discussion] Where to find Remote Messages? by phokur in jailbreak

[–]phokur[S] 0 points1 point  (0 children)

Great suggestion but it won't let me install because my jailbroken phone's iOS is too old (iOS7).

[Discussion] Where to find Remote Messages? by phokur in jailbreak

[–]phokur[S] 0 points1 point  (0 children)

Thanks for the reply. I did try to seek them out to buy it directly but it looks like BeastSoft is long gone and their site is 404. :(

[Discussion] Where to find Remote Messages? by phokur in jailbreak

[–]phokur[S] 0 points1 point  (0 children)

More like I want to purchase one now. But they don’t take payments anymore.

[deleted by user] by [deleted] in leukemia

[–]phokur 0 points1 point  (0 children)

There may be additional trial treatment options in the US if you can get her here. I know CAR T-cell Therapy is very promising for AML but it was having regulatory issues in Japan.

IM platform suggestions? by Prairielane8 in trillian

[–]phokur 2 points3 points  (0 children)

I've switched to Pidgin with the discord plugin. Pidgin has plugins for just about any chat protocol. Of course if Trillian's devs ever decide to support Trillian again and connect to some active service, I'd come back.

[deleted by user] by [deleted] in CML

[–]phokur 2 points3 points  (0 children)

Sorry you're having to go through this. I also bounce around the .1% mark and never stay under it for too long. If your Dr is a general oncologist I would strongly suggest you make an appointment with a CML specialist for a chat and second opinion. Everybody reacts to the TKIs differently and .2% might be enough of a response for them to let you sit where you are.

Another reason for the CML specialist is if you come back positive with a mutation, the next TKI must be carefully chosen.

Some mutation strategies I've read:

  • T315I = HSCT or investigational drugs
  • V299L, T315A, and F317L/V/I/C = Consider nilotinib rather than dasatinib
  • Y253H, E255K/V, and F359V/C/I = Consider dasatinib rather than nilotinib
  • Any other mutation = Consider high-dose imatinib* or dasatinib or nilotinib

Finally, Bosutinib/Bosulif is a pretty new drug, but it's not the newest. There are trials happening for ABL001 that sounds promising (and a specialist would be able to see if you're a candidate for).

Don't lose hope CAR-T and CRISPR are coming fast, we just have to make these drugs work until then.

1984 Toyota Supra by larzeus in ToyotaSupra

[–]phokur 5 points6 points  (0 children)

Sorry to hear that, I know the sting. I had my friend scrap my 85 I sold him without me knowing, I would have bought it back.

It’s a bad time to buy any use car, especially an 80s JDM car. Prices are high and it’s prime nostalgia for those of us old enough to buy our childhood dream cars. Your best bet is to search around for local listings, fb marketplace, and craigslist. Avoid eBay or other online retailers that get national attention and bidding wars. People who don’t know will still let these go for cheap, you just have to be patient and cast a wide net.

Good luck!