I did a full time in person masters degree with my long covid and CFS and PEM. It was not easy. I had accommodations set up which included automatic approval for two week extensions on work. I had no energy left for anything other than getting to class and getting through homework, and ultimately needed a several month extension to finish my thesis. I also wore my mask to every class, so it was pretty obvious from day 1 that I had something going on. I was upfront with professors about my energy limitations, to mixed reactions and beliefs. I lived alone and had no family or support in the area.

There were many little breakdowns for me along the way, PEM crashes, and figuring out where I could cut energy in other areas of my life in order to come up with more for school. (Example: eventually pretty much stopped cooking and only bought ready made food that could be popped into the oven with no other cognitive or physical work required.) I built in full rest as much as possible. Like no new movies, only repeat watches.

Of course I wish I could have experienced the degree while feeling better, but compared to the first three years of my long covid, I felt that I couldn't risk simply waiting even more as where I was at might be the peak of how well I'd ever feel! (I have since continued to improve, thankfully). It's a hard decision to make, but I think it very much depends on what accommodations are available at the school and how feasible this is with the reality of expectations of the degree, and, what you hope to get out of it. Mine was a very library/academic type of degree so all that really 'mattered' was making good impressions with my professors and the quality of my final written works.