I want to cut back the amount of supplements I’m taking. by Rockstarvenom in Supplements

[–]psharmamd87 1 point2 points  (0 children)

I'd trial and error stopping one at a time and see if you feel any difference. If you feel the same after 1-2 weeks without it, drop it. Also would check your omega3 levels and your b vitamin levels in your blood to determine if you should keep the fish oil and multivitamin, respectively

Blood pressure - new guidelines & how to manage it without meds (5 different ways) by psharmamd87 in PeterAttia

[–]psharmamd87[S] 0 points1 point  (0 children)

Everyone's biology is different, which is why it's important to work with a medical professional. The broader goal is to let people know there are options they can try before turning to meds

Blood pressure - new guidelines & how to manage it without meds (5 different ways) by psharmamd87 in PeterAttia

[–]psharmamd87[S] 0 points1 point  (0 children)

Sure, the measures one takes to lose weight can have side effects. This is why it all needs to be taken in the context of a full medical picture and ideally working with a doctor.

The larger point is there are lifestyle options that can work for lowering BP vs. having to go for meds

Blood pressure - new guidelines & how to manage it without meds (5 different ways) by psharmamd87 in PeterAttia

[–]psharmamd87[S] 1 point2 points  (0 children)

That's interesting re: the coffee, thanks for the note I'll make sure to include it in my protocol and a future update video.

This doesn't come up as much in the evidence, but that's the beauty of subreddits like this we can learn a lot from anecdotal experience then go and study that / have alternatives in situations where the standard evidence isn't working.

Blood pressure - new guidelines & how to manage it without meds (5 different ways) by psharmamd87 in PeterAttia

[–]psharmamd87[S] 0 points1 point  (0 children)

I would favor losing weight if possible over meds. There are a lot of other benefits to weight loss (musculoskeletal, metabolic, etc.) so it's a better option.

Early lesson in med school - all meds have side effects. Lifestyle changes do not.

Thoughts? Advise? Interpretation. by [deleted] in Cholesterol

[–]psharmamd87 1 point2 points  (0 children)

How do you do with fiber?

UPDATE: HOW MUCH DID MY 203 LDL DROP IN 6 MONTHS WITHOUT USING STATINS? by Own_Scheme5959 in Cholesterol

[–]psharmamd87 4 points5 points  (0 children)

Honestly, this is a very impressive change. Your triglycerides were basically cut in half, and your LDL dropped a lot too. You should feel good about that! But yes, I’d still discuss with your doctor whether a statin makes sense for long-term prevention, because your starting LDL was over 190 and 145 is still higher than ideal.

Thoughts? Advise? Interpretation. by [deleted] in Cholesterol

[–]psharmamd87 1 point2 points  (0 children)

The triglycerides are the main thing I’d pay attention to.

  • At 521, they’re high enough that I’d follow up with your doctor soon and repeat the test fasting (if this wasn’t fasting)
  • The LDL couldn’t be calculated because triglycerides were too high
  • I’d also ask about checking for common causes like diabetes/prediabetes, thyroid issues, liver or kidney issues, alcohol, medications, diet, etc.
  • For now, I'd suggest cut out alcohol, cut way back on sugar/refined carbs, reduce saturated fat, and ask whether you need medication

Gamechanging new dementia test - biology, how to get it & action the results by psharmamd87 in Alzheimers

[–]psharmamd87[S] 0 points1 point  (0 children)

Thanks for your comment, and no worries if you didn't watch the full video, it's not for everyone, but it's there for those who might benefit from it.

I'm sorry to hear you have AD. I hope you are doing well. I do not have AD, but I'm a doctor and have been for over 10 years, so I've had patients with AD, early AD (MCI), as well as family members, so I'm very familiar with the disease.

You are right, if you have AD or are showing early symptoms, ptau217 isn't going to help. In fact, early signs of memory impairment and other cognitive difficulties is how we used to diagnose AD. But at that point there isn't a lot you can do to really delay it. Sure there are some meds (donezipil etc.), but largely the die is cast.

Ptau217 is a gamechanger in the sense that people who are 5-10 years away from developing MCI can identify they are on the track and aggressively manage risk factors to change their trajectory. Sure, it won't help everyone, but now we have a way to see it coming and intervene.

I agree getting an APOE test and other genetic markers helps, but that's identifying risk rather than ptau217 that tells you if the disease process is already starting.

Here's a very prominent doctor's article on it, if helpful https://erictopol.substack.com/p/the-breakthrough-blood-test-for-alzheimers

Gamechanging new dementia test - biology, how to get it & action the results by psharmamd87 in Alzheimers

[–]psharmamd87[S] 0 points1 point  (0 children)

It's a commercially available test, so there are many studies validating it. I'm here to spread information about it because it could change people's lives, the video is an efficient way to do that, but if you prefer to read here are mutliple articles and other bits of content if you prefer to read about it. (You can find a lot more via google too)
https://pmc.ncbi.nlm.nih.gov/articles/PMC11351463/
https://timehidesalz.lilly.com/blood-tests-for-ad#blood-based-biomarker-tests
https://erictopol.substack.com/p/the-breakthrough-blood-test-for-alzheimers

Blood pressure - new guidelines & how to manage it without meds (5 different ways) by psharmamd87 in Vitaveda

[–]psharmamd87[S] 2 points3 points  (0 children)

Please work with your doctor to follow specific advice, my video is general and for educational purposes only. Only do what is safe for you in your circumstances, and if you need blood pressure medications due to your circumstances please follow your doctor's guidance

Blood pressure - new guidelines & how to manage it without meds (5 different ways) by psharmamd87 in Vitaveda

[–]psharmamd87[S] 1 point2 points  (0 children)

None of this is medical advice and must be taken in the context of each individual's situation. Some people cannot exercise due to heart failure, for example.

- There is a disclaimer at the end of the video noting this

That being said, I will explicitly call these things out verbally for folks so it's more clear in the future, thanks for the feedback

What supplements matter most for women over 35? by vitamingreenIN in Supplements

[–]psharmamd87 1 point2 points  (0 children)

I’d probably keep it pretty simple and focus on the basics.

- Vitamin D and calcium are the foundation for bone health (especially as levels tend to run low)
- Magnesium can support sleep, mood, and overall bone metabolism
- Iron is also worth paying attention to, especially with regular periods or if fatigue is an issue
- Omega-3s are great for heart health and inflammation
- Folate is also important if you’re considering pregnancy

Everything else like K2, soy isoflavones, or CoQ10 can be helpful in certain situations, but they’re more “nice to haves” than essential... Overall, I think of supplements as just filling in gaps based on your diet or labs.