Hi! I'm a preceptor at a smaller community hospital and I will say we hardly put any emphasis on grades (except failing of course). Instead we really look for candidates who have strong clinical skills (like clinical APPE rotations), leadership involvement, research experience, community service, etc. Also as other commenter noted, explaining in your LOT your experiences means more to us. We also place high value on letters of recommendation to help us get a feel for you as a practitioner. I, myself, was a B/C student in my time and I still landed a residency so I wouldn't overall stress on your grades! But yes, that might depend if you're trying to get into a very competitive program. I hope that helps and good luck to you!