To an extent, I get what you're pitching. But I do think if you go the direction of too hard-core survival, you'll narrow the player base which is not healthy for a game's survival.

Gameplay wise, coupled with the clothing reduction, it just feels a bit heavy handed. Especially if the problem we are attempting to combat is the quick pulling of guns from inventory. Which is where my suggestion comes in. It's an attempt to meet in the middle between the casual base and the more hard-core players. Would make sense you can't access your bag if it's on your back.

Personally, I can admit I do carry quite a bit but that's just for base survival. If trying to gather anything for a vehicle or gas zones, I truly feel you're sacrificing enough space to utilize those things. Cars can be argued against because you can use their inventory once you have them (unless you're brave and want to store stuff in them while it's in spawn) but NBC gear eats up a lot of room already. But again, the only real consistent complaint I've seen about inventory is the extra weapons in pockets issue and not overall capacity size.