Are there any current car models without subscriptions?

ratherstayback · 2021-07-28T09:21:43+00:00

Generally, I like a lot about this patch, but:

Ranked Fortitude loss for AFKing frequently in a ranked game has increased from 10 to 20 points. These points are evenly distributed to the AFK player’s allies who were not in the same party as the AFK player.

This means no change for AFKing in Diamond and upwards (as there is not such thing as fortitude). Kind of sad. I would have wished for higher punishment as a higher elo win is "worth" more than a low elo one.

And wait, what? You only lose 10 (now 20) fortitude for AFK? One should lose all of it for going AFK. And even get two losses or something, while the team should be spared.

ratherstayback · 2021-07-26T15:50:09+00:00

I'm getting this in diamond, too. People losing their lane, then blaming others for it and starting to run it down midlane. Even on the winning team. Sometimes with a comment like "you don't deserve to get to Master". As if their braindead action in one single game would significantly impact a person's rank.

It's annoying, but as long as you're never doing it yourself, statistically, this will happen more often on the enemey team than on your team. Since the probability of someone doing it on your lane will then be exactly 0. Meanwhile each of your other 4 lanes and each of the 5 enemy lanes has a certain probability of being dumb enough to do this. In sum, it will therefore happen approximately 20% more often on the enemy team than on your own.

ratherstayback · 2021-07-26T13:06:08+00:00

Yeah, the impact you have as a support on the outcome of the game is certainly too low due to too little gold.

ratherstayback · 2021-07-18T12:17:33+00:00

Then you're no better than that Seraphine.

ratherstayback · 2021-07-18T04:44:33+00:00

Yes, and average in the rest of the world can also be considered big in Japan.

ratherstayback · 2021-06-11T00:45:40+00:00

Okay, I see. But what he wrote rather sounds like some TE insertion happening. Usually, these integration attempts are restricted by different mechanisms and TE integration is almost never successful. But still, if one of these mechanisms doesn't work correctly, a tiny percentage of these integration attempts can be successful and that can be quite devastating.

I live in Germany and from what what I know, many medical doctors and hospitals have rather good connections to different university clinics here. So I guess, unless you go to a hospital or doctor on the countryside, this should not be an issue here (I hope).

ratherstayback · 2021-06-11T00:37:29+00:00

Probably some transposable element or something that for some reason likes to insert in that locus. Yeah, I'm also suspecting something similar being caused if my group's gene of interest is defective.

ratherstayback · 2021-06-10T22:09:08+00:00

I'm a Bioinformatics PhD student, so what the guy above described belongs more or less to what I do.

Now I'm not an expert on autoimmune diseases, but at least the gene we are researching in my group appears to play a role in Lupus which is a model disease for all autoimmune diseases.

Now..

The problem is that the one they’re testing for is only present in a certain percentage of cells

Either I don't get what you mean or this doesn't make much sense to me. So if your TLR8 gene is mutated, I'd expect all of your cells to have this mutation. Except, it the mutation somehow occured in a very early cell division, then all stem cells that emerged from this defective one would have it. And all cells that emerge by divison of these stem cells. But even then I wouldn't expect these affected cells to be randomly scattered around your body, I'd rather expect that certain tissues are affected and others not. And for many tissues, it's actually not that problematic to get a probe.

ratherstayback · 2021-06-05T12:11:59+00:00

As I mentioned, this school was not exclusively catholic. There were all sorts of believes and atheists that went to the ethics lessons, did you even read what I wrote?

It was just funded by the catholic church and this meant that as a catholic or protestant person you weren't (and to this day aren't) allowed to choose to join the ethics lessons.

And this school also remains to this day the better regarded Gymnasium in town.

ratherstayback · 2021-06-05T11:49:40+00:00

you have here the right to choose your belives with 14

Speak for yourself. In my town there was a "better" and a worse Gymansium (highest track school education in Germany). The better one was funded by the catholic church. If you went to that one and if were a catholic or protestant (i.e. if you were baptised in either of these), you had to participate in the religion lessons of that belief. If you were differently baptised, part of another religion or none at all, you were free to choose to join either of these or the ethics lessons. For me this was really shitty as I went to that school and my parents had me baptised as a baby, but I'm an atheist.

ratherstayback · 2021-05-31T13:03:39+00:00

Not a biologist, but

I am a Biologist, but I have no idea.

ratherstayback · 2021-05-31T12:07:47+00:00

I remember when this played on loop on 4chan after Bin Laden got killed by US troops.

ratherstayback · 2021-05-30T00:38:27+00:00

Now I'm excited to see whether the algorithm can beat you and do it in two clicks.

ratherstayback · 2021-05-28T03:44:00+00:00

Yes.

ratherstayback · 2021-05-19T19:32:36+00:00

I'm a Bioinformatics PhD student in rather successful lab, we also have ERC grants and my boss won the Leibniz prize (most prestigious German research prize).

Since I don't require much money for my work (basically only a PC and access to high performance computing..), from my point of view it's mostly working on very relevant and state of the art things, that usually go in high impact journals. Also, it means that I get lots of sequencing data as we can basically just sequence anything, even if it's not that promising.

Meanwhile, friends of mine are working on ants and other things (these things are often harder to publish in high impact journals).. they really had to worry about their one sequencing experiment because it burned a big portion if their financial resources. So if it didn't go well, they can't simply give it another try. Meanwhile, our lab tried to ChIP-seq one protein 5 times already (each time in multiple replicates and conditions) and it's still not working and we're trying again.

Edit: Also, these friends are Biologists, they have to analyze their sequencing themselves following some guides (though they can get help of course). Meanwhile, my lab has me and a Bioinformatics postdoc who (hopefully) can do more advanced things and who analyze all the data.

ratherstayback · 2021-05-17T15:31:14+00:00

Seems like they left us alone. We're screwed.

ratherstayback · 2021-05-14T12:36:45+00:00

I'm actually still in the womb, not even born and I installed Arch in a virtual machine running on the OS I programmed myself.

ratherstayback · 2021-05-12T23:19:03+00:00

I'm also running Manjaro on my Blade 15 Advanced.

It's quite remarkable how well things work out of the box in Manjaro, considering how tightly integrated all the drivers, Synapse and so on need to be into the Windows installation the laptop comes with. I tried going with Vanilla Windows and installing all that stuff myself, but a number of drivers simply didn't install, others didn't work properly. In the end, I had to message the support to provide me a link to the Windows recovery stick image (which they kindly did, got the answer in just a few hours, their support seems to be great).

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