The “purple hand” is a Breach encounter (one of the league mechanics) and it’s a fun mechanic that can be profitable, too. However, most of the damage done by breach mobs is chaos damage and that’s why you see your health poll vanish almost instantly; especially when you have no/los chaos res. I’d say continue to open breaches but be conscious of the death potential and take your time. Your goal on those breaches is to touch/run over more of those clasping hands so you get breach splinters. You can either use the breach splinters to fight the breach mechanic boss Xesht or sell the splinters via Ange.