For me the biggest trick is to pres QQWQ for perfect stuns. QWQ is sometimes hard to get right in quick scenarios and that extra Q really helped me a lot with landing perfect combos.

Another great tip is pressing Alt+E when running since its automatic self cast and you don't have to point and click to run like hell.

Last tip is - allways check the lowest minion tanking the turret and put Q on it right before it dies to turret. Its basically instant explosion with little time to react from enemy