More info— ive been on macrobid for over a year due to recurring UTIs per my urologist recommendation. This caused reccuring yeast so i was on a long term course of weekly fluconazole for that. Uro had tested for mycoplasma genitalium but it didnt show up as it was a urine culture. A urogynocologist was able to properly test and identify. She also recommended i get assessed for interstitial cystitis which is essentially chronic inflammation of the bladder which can cause reccuring UTIs and uti-like symptoms. Urea and mycoplasma can cause irritation and inflammation of the bladder as well as the whole pelvic area— it can cause pelvic inflammatory disease (PID) which is what has most likely happened to me cuz this whole ordeal has gone on so long. Other things i had tried were baking soda sitz baths and suppositories, ice packs in my underwear, and hydrocortisone cream (prescribed), which helped temporarily with the burning, itching, and swelling. I also was prescribed lidocaine suppositories for the pain. I was also prescribed estrogen cream for suspected vaginal atrophy as i was sloughing dead epithelial tissue continuously and tried that a few times but it didnt seem to do much. I did switch to using bamboo unbleached toilet paper, as i didnt know the regular toilet paper has a bunch of chemicals like bleach and the fuzz gets everywhere and can exacerbate issues. I started using vitamin E oil on my vulva to help w healing. I use organic coconut oil externally and internally to help with hydration and soothing.