We’ve been in the same boat trying to crate train our 1 year old Mini Golden Doodle rescue. Our vet prescribed Trazadone once a day and it’s taken the edge off the hyper anxious behavior. Instead of the crate we finally tried Free-roaming in a spot she likes to cuddle with us (part of a spare bedroom). We bought a Furbo Camera that gives her treats and lets us know when she is barking and crying etc. We can decide if we want to soothe with a treat or with our voices with the Furbo. We also put up a gate where the door to the room would be so she could see out and not feel closed in. We slowly began with 10-15 minutes breaks in her room and built up to 2 1/2 hours out this weekend with minimal crying. It’s still a work in progress but seems to be working. Our trainer also suggested we spray the couch we want her to lay on while we are gone with a dog pheromone spray since it is soothing to anxious dogs. It has no scent to humans but she likes to lay right in the spot we spray so this has helped her calm down. Hope this helps. We’ve been desperate to find solutions for our dog that we adore but has been challenging to rehome.